Results 81 to 90 of about 192,370 (262)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Modelling and Prediction of Cutting Temperature in the Machining of H13 Hard Steel of Transient Heat Conduction. [PDF]

Materials (Basel), 2021
Zhang J, Meng X, Du J, Xiao G, Chen Z, Yi M, Xu C.   +6 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Simulation and Experimental Research on the Longitudinal–Torsional Ultrasonic Cutting Process Characteristics of Aramid Honeycomb Materials

Applied Sciences
Aiming at the problems of large cutting force, easy honeycomb tearing, and deformation during the traditional cutting process of aramid honeycomb materials and an increase in cutting temperature during continuous processing, which may lead to vibration ...
Mingxing Zhang, Xinpeng Zhang, Linbin Li, Yuzhu Zhang, Liyuan Fang, Ting Meng, Xiaodong Wang   +6 more
doaj   +1 more source

Coating-thickness-dependent physical properties and cutting temperature for cutting Inconel 718 with TiAlN coated tools. [PDF]

J Adv Res, 2022
Zhao J, Liu Z, Ren X, Wang B, Cai Y, Song Q, Wan Y.   +6 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Investigation of the effects of machining parameters on cutting conditions during orthogonal turning of austenite stainless steel

Production Engineering Archives
The 1.4306 austenite stainless steel has been prominently utilized as a material in the automotive and aerospace industry. Considerable interest has been garnered in the machinability of stainless steel owing to its high strength and poor thermal ...
Kónya Gábor, Takács János, Miskolczi István, Kovács Zsolt F.   +3 more
doaj   +2 more sources

Analysis of Thermal Aspect in Hard Turning of AISI 52100 Alloy Steel Under Minimal Cutting Fluid Environment Using FEM

Applied Mechanics
This paper describes a simulation study on the hard turning of AISI 52100 alloy steel with coated carbide tools under minimal cutting fluid conditions using the commercial software AdvantEdge.
Sandip Mane, Rajkumar Bhimgonda Patil, Mohan Lal Kolhe, Anindita Roy, Amol Gulabrao Kamble, Amit Chaudhari   +5 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source