Results 91 to 100 of about 892,705 (358)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Effect of Shift in Speed Turning on Machined Surface Quality
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2017 This article describes the evaluation of machined material roughness in speed turning on a machining centre Doosan Puma 700 LY. The machined surface of semi-finished products from steel 14 260 was compared at selected cutting conditions.
Pavel Polák +2 more
doaj +1 more source
Atomistic aspects of ductile responses of cubic silicon carbide during nanometric cutting [PDF]
, 2011 Cubic silicon carbide (SiC) is an extremely hard and brittle material having unique blend of material properties which makes it suitable candidate for microelectromechanical systems and nanoelectromechanical systems applications.
Goel, Saurav +4 more
core +2 more sources
Transactions of the Japan Society of Mechanical Engineers, 1957 Several experimental results of a research on ceramics as cutting tools are described in this paper. Mechanical properties, grinding pocedures, cutting characteristics and tool life of ceramics are discussed comparing with those for carbide tools. These results showed that ceramic tools used in this study was inferior a little in hardness, sharpness of
Makoto Okoshi, Toshio Sata
openaire +2 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
An investigation on the mechanics of nanometric cutting and the development of its test-bed [PDF]
, 2003 The mechanics of machining at a very small depth of cut (100 nm or less) is not well understood. The chip formation physics, cutting forces generation, resulting temperatures and the size effects significantly affect the efficiency of the process and ...
Cheng, K, Guo, XJ, Holt, R, Luo, X
core +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Multiobjective Optimization of Tool Geometric Parameters Using Genetic Algorithm
Complexity, 2018 Tool geometric parameters have a huge impact on tool wear. Up to now, there are only a few researches on tool geometric parameters and optimization, and the single objective function of parameter optimization used by researchers during high-speed ...
Maohua Du +3 more
doaj +1 more source
Wasit Journal of Engineering Sciences, 2013 The aim of the work is to study the effect of cutting condition on cutting bit of the turning machine while working on different metal ,Through using a special type of commonly used cutting tool bit in (HSS) due to the high qualifications it is ...
Niema H Elmosawi +2 more
doaj +1 more source
Analysis of cutting parameters in point machining of parts with complex shape [PDF]
, 2018 This paper presents developed SW module in the postprocessor, which is designed to backward analysis of CAM milling toolpath. The module is designed to analyze multi-axis finishing machining of complex shape parts with milling cutters with a circular ...
Rybín J. +3 more
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