Results 91 to 100 of about 130,193 (229)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Influence of the Ti-TiN-(Y,Ti,Al)N Nanolayer Coating Deposition Process Parameters on Cutting Tool Oxidative Wear during Steel Turning. [PDF]

Nanomaterials (Basel), 2023
Vereschaka A, Sotova C, Milovich F, Seleznev A, Sitnikov N, Shekhtman S, Pirogov V, Baranova N.   +7 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Transfer Learning-Based Condition Monitoring of Single Point Cutting Tool. [PDF]

Comput Intell Neurosci, 2022
Naveen Venkatesh S, Arun Balaji P, Elangovan M, Annamalai K, Indira V, Sugumaran V, Mahamuni VS.   +6 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Research on the influence of cutting thickness on CFRP material removal behavior considering tool wear

Journal of Materials Research and Technology
Small cutting thicknesses are commonly employed to minimize surface damage during the CFRP finishing process. However, reducing cutting thickness is not always beneficial to surface quality and the cutting process, particularly in cases involving tool ...
Xuda Qin, Yonghua Gao, Pengfei Kang, Shipeng Li, Hao Li, Qing Zhao, Anxin Sun   +6 more
doaj   +1 more source

Evaluating CNC Milling Performance for Machining AISI 316 Stainless Steel with Carbide Cutting Tool Insert. [PDF]

Materials (Basel), 2022
Equbal A, Equbal MA, Equbal MI, Ravindrannair P, Khan ZA, Badruddin IA, Kamangar S, Tirth V, Javed S, Kittur MI.   +9 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Analysis of Cutting Tool Modification Effect toward Force, Power and Temperature at Cutting of Material St 42

Jurnal Energi Dan Manufaktur, 2012
Until now, research by using of a standard cutting tool at lathe process is still become a subject of many studies in order to reduce of the force, cutting power and temperature. However, there are no satisfactory results yet as expected.
I Gusti Komang Dwijana
doaj