Results 101 to 110 of about 942,686 (360)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Expert System Based on Integrated Fuzzy AHP for Automatic Cutting Tool Selection
Applied Sciences, 2019 Cutting tool selection plays an important role in achieving reliable quality and high productivity work, and for controlling the total cost of manufacturing.
Xuan Lan Phung +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
, 2023 verviewStatsCommentsCitationsReferencesRelated research (10+) Share More Beta Want to get 4x more reads of your article? Showcase your recent work in a Spotlight to get 4x more reads on average. Learn more Create Spotlight Abstract During chip formation process of machining operations, thermo-mechanical loads are generated which can decrease life of ...
Soori, Mohsen, Arezoo, Behrooz
openaire +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Indirect monitoring method of tool wear using the analysis of cutting force during dry machining of Ti alloys [PDF]
, 2017 In recent decades, optimize tool life is in constant evolution so many researchers have focused to analysis the tool wear by indirect monitoring (e.g. acoustic emission, cutting forces, vibrations) that plays a significant role in control and improvement
Marcos, Mariano +3 more
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Atomistic aspects of ductile responses of cubic silicon carbide during nanometric cutting [PDF]
, 2011 Cubic silicon carbide (SiC) is an extremely hard and brittle material having unique blend of material properties which makes it suitable candidate for microelectromechanical systems and nanoelectromechanical systems applications.
Goel, Saurav +4 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Displacements analysis of self-excited vibrations in turning
, 2009 The actual research deals with determining by a new protocol the necessary parameters considering a three-dimensional model to simulate in a realistic way the turning process on machine tool.
A Cowley +26 more
core +1 more source