Results 111 to 120 of about 892,705 (358)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Indirect monitoring method of tool wear using the analysis of cutting force during dry machining of Ti alloys [PDF]

open access: yes, 2017
In recent decades, optimize tool life is in constant evolution so many researchers have focused to analysis the tool wear by indirect monitoring (e.g. acoustic emission, cutting forces, vibrations) that plays a significant role in control and improvement
Marcos, Mariano   +3 more
core   +1 more source

The Effect Of The Tool Geometry And Cutting Conditions On The Tool Deflection And Cutting Forces

open access: yes, 2010
In this paper by measuring the cutting forces the effect of the tool shape and qualifications (sharp and worn cutting tools of both vee and knife edge profile) and cutting conditions (depth of cut and cutting speed) in the turning operation on the tool deflection and cutting force is investigated.
A. Fata, B. Nikuei
openaire   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Performance comparison and prediction of cutting energy of new cemented carbide micro-pit turning tool

open access: yes工程科学学报, 2017
Cutting energy can be transformed into cutting heat, which directly affects the cutting temperature. Therefore, it is important to understand the generation, transfer, and transformation of cutting energy to cutting temperature.
ZHAN Gang   +3 more
doaj   +1 more source

Design of an instrumented smart cutting tool and its implementation and application perspectives [PDF]

open access: yes, 2014
This paper presents an innovative design of a smart cutting tool, using two surface acoustic wave (SAW) strain sensors mounted onto the top and the side surface of the tool shank respectively, and its implementation and application perspectives.
Chen, X   +4 more
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

THERMAL PROCESSES RESEARCH DEVELOPMENT IN MACHINE-BUILDING TECHNOLOGY

open access: yesЗаписки Горного института, 2018
The technique for determining the temperature in the surface layer of the workpiece with a blade tool is considered, taking into account the volume heat source in the cutting zone, on the basis of which it is proposed to calculate the processing errors ...
V. F. Bez"yazychnyi, M. Scherek
doaj   +1 more source

Displacements analysis of self-excited vibrations in turning

open access: yes, 2009
The actual research deals with determining by a new protocol the necessary parameters considering a three-dimensional model to simulate in a realistic way the turning process on machine tool.
A Cowley   +26 more
core   +1 more source

123. Egyptian Cutting-Out Tools. [PDF]

open access: green, 1901
William Matthew Flinders Petrie
openalex   +1 more source

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