Results 51 to 60 of about 867,518 (339)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Indirect Adhesion Wear Parametric Analysis in the Dry Turning of UNS A97075 Alloys [PDF]

, 2017
In this work a study of the influence of cutting parameters (cutting speed, feed and depth of cut) on indirect adhesion tool wear in the dry machining of UNS A97075 Al-Zn alloys has been made. In addition, an experimental methodology for a first approach
Marcos Bárcena, Mariano, Martín Béjar, Sergio, Sevilla-Hurtado, Lorenzo, Trujillo Vilches, Francisco Javier   +3 more
core   +1 more source

Photographs of Cutting-Tools in Action [PDF]

Proceedings of the Institution of Mechanical Engineers, 1905
n ...
openaire   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

A Comparative Study of Tool Wear for Niobium Carbide and Tungsten Carbide-Based Cutting Materials in Dry Cylindrical Turning

Journal of Machine Engineering
Using niobium carbide (NbC) for cutting materials is a promising alternative to tungsten carbide (WC) based cutting materials for metal machining due to the inherent material properties of NbC.
Eckart Uhlmann, Christoph Schneider
doaj   +1 more source

Study on the Cutting Performance of Micro Textured Tools on Cutting Ti-6Al-4V Titanium Alloy

Micromachines, 2020
Titanium alloys are widely used in various fields, but their machinability is poor because the chip would easily adhere to the tool surface during cutting, causing poor surface quality and tool wear.
Kairui Zheng, Fazhan Yang, Na Zhang, Qingyu Liu, Fulin Jiang   +4 more
doaj   +1 more source

A performance of 2 dimensional ultrasonic vibration assisted milling in cutting force reduction, on aluminium AL6061 [PDF]

, 2016
This paper were investigate a performance of 2 Dimensional Ultrasonic Vibration assisted Milling (UVAM) toward Aluminium Al 6061. The focus is to find the performance of reduction of cutting force compared to the conventional machining in the industries ...
Abd. Rahim, Erween, Hui, Ding, Ibrahim, Rasidi, Kai, Cheng, Rafai, Noor Hakim   +4 more
core  

Cutting-Edge Tools for Cutting Edges

23 pages, invited contribution to the Encyclopedia of Mathematical ...
Britto, Ruth, Duhr, Claude, Hannesdottir, Holmfridur S., Mizera, Sebastian   +3 more
openaire   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source