Results 51 to 60 of about 397 (126)

Pathogenicity and Pathotype Analysis of Henan Isolates of Marek’s Disease Virus Reveal Long-Term Circulation of Highly Virulent MDV Variant in China

Viruses, 2022
In recent years, outbreaks of Marek’s disease (MD) have been frequently reported in vaccinated chicken flocks in China. Herein, we have demonstrated that four Marek’s disease virus (MDV) isolates, HN502, HN302, HN304, and HN101, are all pathogenic and ...
Man Teng, Lu-Ping Zheng, Hui-Zhen Li, Sheng-Ming Ma, Zhi-Jian Zhu, Shu-Jun Chai, Yongxiu Yao, Venugopal Nair, Gai-Ping Zhang, Jun Luo   +9 more
doaj   +1 more source

Molecular and pathological investigations of Marek’s disease outbreaks in vaccinated poultry farms in Plateau State, North Central-Nigeria [PDF]

, 2022
Marek’s disease (MD) is a devastating neoplastic disease of poultry caused by MD virus (MDV). MD is one of the several diseases limiting the thriving Nigerian poultry industry.
Abdu, Paul, Adedeji, Adeyinka, Akanbi, Olatunde, Luka, Pam   +3 more
core   +1 more source

Pathology and Molecular Diagnosis of Marek’s Disease Virus in Chickens in Nigeria

Scientifica, Volume 2025, Issue 1, 2025.
Marek’s disease caused by Marek’s disease virus (MDV) serotype 1 is an economically important neoplastic disease of poultry. Diagnosis of this disease is usually based on clinical signs, postmortem lesions, and diagnostic tests like cytology, histopathology, and molecular‐based methods.
Olusegun Adesina Fagbohun, Aiki-Raji Comfort Oluladun, Theophilus Aghogho Jarikre, Olugbenga Olayinka Alaka, Ademola Adetokunbo Oyagbemi, Rofiat Damilola Adesina, Oluwaseun Olanrewaju Esan, Olumide Odunayo Akinniyi, Moses Olusola Adetona, Temidayo Olutayo Omobowale, Ufuoma Joan Mamoh, Ishmael Festus Jaja, Amir Sasan Mozaffari Nejad   +12 more
wiley   +1 more source

Safety and Efficacy Evaluation of Recombinant Marek’s Disease Virus with REV-LTR

Vaccines, 2020
Recently, chickens vaccinated with the CVI988/Rispens vaccine showed increased tumor incidence. Moreover, many strains of Marek’s disease virus (MDV) that were naturally integrated with the long terminal repeat (LTR) of the avian reticuloendotheliosis ...
Cuiping Song, Yang Yang, Jing Hu, Shengqing Yu, Yingjie Sun, Xvsheng Qiu, Lei Tan, Chunchun Meng, Ying Liao, Weiwei Liu, Chan Ding   +10 more
doaj   +1 more source

The Meq Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains [PDF]

Background: Marek’s disease (MD) is a pathology affecting chickens caused by Marek’s disease virus (MDV), an acute transforming alphaherpesvirus of the genus Mardivirus.
Jwander, Luka, Kaufer, Benedikt B., Ladman, Brian, Mbachu, Ifeoma, Parcells, Levi, Parcells, Mark S., Patria, Joseph N., Tavlarides-Hontz, Phaedra, Trimpert, Jakob   +8 more
core   +1 more source

Regulation of Wnt/β-catenin signaling by Marek’s disease virus in vitro and in vivo

Frontiers in Microbiology
Marek’s disease virus (MDV) infection causes immunosuppression in the host, ultimately inducing tumor formation and causing significant economic losses to the poultry industry.
Haiyin Xu, Haiyin Xu, Xihao Xu, Xihao Xu, Huifeng He, Huifeng He, Hongxia Shao, Hongxia Shao, Hongxia Shao, Yongxiu Yao, Aijian Qin, Aijian Qin, Aijian Qin, Kun Qian, Kun Qian, Kun Qian   +15 more
doaj   +1 more source

Marek’s Disease Virus Modulates T Cell Proliferation via Activation of Cyclooxygenase 2-Dependent Prostaglandin E2 [PDF]

, 2021
Copyright © 2021 Kamble, Gurung, Kaufer, Pathan and Behboudi. Marek’s disease virus (MDV), an avian alphaherpesvirus, infects chickens, transforms CD4+ T cells, and induces immunosuppression early during infection.
Behboudi, S, Gurung, A, Kamble, N, Kaufer, BB, Pathan, AA   +4 more
core   +2 more sources

Differential amplification of Marek’s disease CVI988 vaccine and of wild-type isolates from organs of commercial chickens using single or duplexed probes in real-time PCR [PDF]

Avian Pathology, 2017
The differentiation of Marek's disease virus (MDV)-infected and vaccinated animal (DIVA) test, based on the MDV pp38 gene was described by Baigent et al. [(2016). Real-time PCR for differential quantification of CVI988 vaccine and virulent MDV strains. Journal of Virological Methods, 233, 23-36], using similar primers and alternate probes for virulent ...
Irit, Davidson, Amira, Natour-Altoury, Israel, Raibstein, Yaad, Dahan   +3 more
openaire   +2 more sources

Application of CRISPR/Cas9 Gene Editing System on MDV-1 Genome for the Study of Gene Function

Viruses, 2018
Marek’s disease virus (MDV) is a member of alphaherpesviruses associated with Marek’s disease, a highly contagious neoplastic disease in chickens.
Yaoyao Zhang, Na Tang, Yashar Sadigh, Susan Baigent, Zhiqiang Shen, Venugopal Nair, Yongxiu Yao   +6 more
doaj   +1 more source

An outbreak in three-yellow chickens with clinical tumors of high mortality caused by the coinfection of reticuloendotheliosis virus and Marek’s disease virus: a speculated reticuloendotheliosis virus contamination plays an important role in the case

Poultry Science, 2021
Both reticuloendotheliosis and Marek's disease are neoplastic diseases of chickens caused by reticuloendotheliosis virus (REV) and Marek's disease virus (MDV), respectively.
Mengya Shi, Min Li, Peikun Wang, Weiwei Wang, Haijuan Li, Yanli Gao, Lulu Lin, Teng Huang, Ping Wei   +8 more
doaj   +1 more source