Results 51 to 60 of about 354 (118)
AbstractThe aim of the study was to determine the influence of adenovirus infection on the replication of Marek’s disease virus vaccine strain Rispens/CVI988 during in vitro co-infection studies. Adenovirus field strain JN-5/10j was isolated from sick chickens. The study was conducted in chicken embryo fibroblast cultures (CEF). Monolayers of CEFs were
J S, Niczyporuk +3 more
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Background Marek’s disease virus (MDV) resides in the genus Mardivirus in the family Herpesviridae. MDV is a highly contagious virus that can cause neurological lesions, lymphocytic proliferation, immune suppression, and death in avian species, including
Xue Lian +8 more
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Construction and characterization of a H19 epitope point mutant of MDV CVI988/Rispens strain.
A recombinant virus, CVI/rpp38, was developed from the Marek's disease virus (MDV) CVI988/Rispens vaccine strain. This recombinant was obtained by transfection of CVI988/Rispens-infected chick embryo fibroblasts (CEFs) with plasmid pHA25 DNA containing pp38 gene from GA strain of MDV. Monoclonal antibody (MAb) H19 which reacts with pp38 from GA but not
Z, Cui +4 more
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This study was designed to investigate the influence of Gallid herpesvirus 2 Marek's Disease challenge virus and different inoculated routes of attenuated vaccine virus CVI988/Rispens on immune adhesion of erythrocytes in chickens. One day old chicks were randomly divided into a control group (C), an experimental group challenged with Jing-1 challenge ...
W.X. Tian +9 more
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GX0101, Marek’s disease virus (MDV) strain with a long terminal repeat (LTR) insert of reticuloendotheliosis virus (REV), was isolated from CVI988/Rispens vaccinated birds showing tumors.
Ning eCui +5 more
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Trials for isolation and identification of Marek's disease virus (MDV) in layer chicken farms vaccinated with MDV vaccines exhibiting MDV-like symptoms in Egypt [PDF]
Marek's disease virus (MDV) is a lymphoproliferative neuropathic disease affecting domestic fowl. Despite intensive vaccination, Egyptian poultry farms continue to experience recurrent infections of MDV.
Alaa H. Ibrahim +3 more
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Background Marek's disease virus (MDV) causes an acute lymphoproliferative disease in chickens, resulting in immunosuppression, which is considered to be an integral aspect of the pathogenesis of Marek's disease (MD).
Cui Zhizhong +5 more
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MDV-1 CVI988/Rispens疫苗毒体外感染期间VP22的表达及细胞间转导作用 [PDF]
利用CVI988 VP22蛋白C端94~243 aa片段作为抗原制备特异性抗体, 并用于检测MDV-1不同毒株感染鸡胚成纤维细胞(CEF)时, 在不同感染时间内的表达情况. 结果发现, 当感染量PFU=50时, MDV各不同致病力的毒株(GA, RB1B和CVI988株)VP22最早在3 h时开始向病毒感染细胞的邻近细胞核内扩散; 8 h时, VP22几乎扩散到所有细胞的核内. 这说明VP22在感染细胞形成空斑之前就已经开始表达, 并高效转导入其他正常的细胞核内. 实验中发现血清I型马立克氏病病毒(MDV-1)弱毒株CVI988/Rispens的VP22蛋白缺失 201 TKSERT 206 .
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High load of oncogenic Marek’s disease virus (MDV) DNA in the feather pulp (FP) as early as 21 days of age is a powerful criterion to predict the outcome of Marek’s disease (MD) in apparently healthy chickens. The objective of this study was to elucidate the immunopathological changes in the FP of 21-days-old chickens that had been vaccinated with ...
Federico C, Bonorino +6 more
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Background Marek's disease (MD) is an economically important viral disease of chickens caused by Marek's disease virus (MDV), an oncogenic herpesvirus. This disease was well controlled since the widespread use of commercial vaccines, but field MDVs have ...
Liu Ping +8 more
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