Results 41 to 50 of about 354 (118)

Protection conferred by a recombinant Marek’s disease virus that expresses the spike protein from infectious bronchitis virus in specific pathogen-free chicken

Virology Journal, 2012
Background In many countries, the predominant field isolates of infectious bronchitis virus (IBV) have been classified as QX-like strains since 1996.
Zhang Xiaorong, Wu Yantao, Huang Yezhen, Liu Xiufan   +3 more
doaj   +1 more source

A Novel Effective and Safe Vaccine for Prevention of Marek’s Disease Caused by Infection with a Very Virulent Plus (vv+) Marek’s Disease Virus

Vaccines, 2021
Marek’s disease virus (MDV) is a highly contagious alphaherpesvirus that causes rapid onset lymphoma in chickens. Marek’s disease (MD) is effectively controlled using vaccination; however, MDV continues to break through vaccinal immunity, due to the ...
Yifei Liao, Sanjay M. Reddy, Owais A. Khan, Aijun Sun, Blanca Lupiani   +4 more
doaj   +1 more source

Safety and Efficacy Evaluation of Recombinant Marek’s Disease Virus with REV-LTR

Vaccines, 2020
Recently, chickens vaccinated with the CVI988/Rispens vaccine showed increased tumor incidence. Moreover, many strains of Marek’s disease virus (MDV) that were naturally integrated with the long terminal repeat (LTR) of the avian reticuloendotheliosis ...
Cuiping Song, Yang Yang, Jing Hu, Shengqing Yu, Yingjie Sun, Xvsheng Qiu, Lei Tan, Chunchun Meng, Ying Liao, Weiwei Liu, Chan Ding   +10 more
doaj   +1 more source

Application of CRISPR/Cas9 Gene Editing System on MDV-1 Genome for the Study of Gene Function

Viruses, 2018
Marek’s disease virus (MDV) is a member of alphaherpesviruses associated with Marek’s disease, a highly contagious neoplastic disease in chickens.
Yaoyao Zhang, Na Tang, Yashar Sadigh, Susan Baigent, Zhiqiang Shen, Venugopal Nair, Yongxiu Yao   +6 more
doaj   +1 more source

Differential amplification of Marek’s disease CVI988 vaccine and of wild-type isolates from organs of commercial chickens using single or duplexed probes in real-time PCR [PDF]

Avian Pathology, 2017
The differentiation of Marek's disease virus (MDV)-infected and vaccinated animal (DIVA) test, based on the MDV pp38 gene was described by Baigent et al. [(2016). Real-time PCR for differential quantification of CVI988 vaccine and virulent MDV strains. Journal of Virological Methods, 233, 23-36], using similar primers and alternate probes for virulent ...
Irit, Davidson, Amira, Natour-Altoury, Israel, Raibstein, Yaad, Dahan   +3 more
openaire   +2 more sources

An outbreak in three-yellow chickens with clinical tumors of high mortality caused by the coinfection of reticuloendotheliosis virus and Marek’s disease virus: a speculated reticuloendotheliosis virus contamination plays an important role in the case

Poultry Science, 2021
Both reticuloendotheliosis and Marek's disease are neoplastic diseases of chickens caused by reticuloendotheliosis virus (REV) and Marek's disease virus (MDV), respectively.
Mengya Shi, Min Li, Peikun Wang, Weiwei Wang, Haijuan Li, Yanli Gao, Lulu Lin, Teng Huang, Ping Wei   +8 more
doaj   +1 more source

A Common Live-Attenuated Avian Herpesvirus Vaccine Expresses a Very Potent Oncogene

mSphere, 2019
Vaccines play a crucial role in the protection of animals and humans from deadly pathogens. The first vaccine that also protected against cancer was developed against the highly oncogenic herpesvirus Marek’s disease virus (MDV).
Andelé M. Conradie, Luca D. Bertzbach, Nirajan Bhandari, Mark Parcells, Benedikt B. Kaufer   +4 more
doaj   +1 more source

The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes

Viruses, 2019
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Luca D. Bertzbach, Florian Pfaff, Viktoria I. Pauker, Ahmed M. Kheimar, Dirk Höper, Sonja Härtle, Axel Karger, Benedikt B. Kaufer   +7 more
doaj   +1 more source

The Meq Gene Molecular Profile of Marek’s Disease Virus Serotype 1 From Kampung and Arabic Chicken Farms in Sukabumi, West Java, Indonesia

Hayati Journal of Biosciences, 2016
There is an increasing trend to use molecular approaches to the study of Marek’s disease virus serotype 1 (MDV-1), the causative agent for the neoplastic syndrome of chickens known as Marek’s disease.
Risza Hartawan, Ni Luh Putu Indi Dharmayanti   +1 more
doaj   +1 more source

Pervasive Differential Splicing in Marek’s Disease Virus Can Discriminate CVI-988 Vaccine Strain from RB-1B Very Virulent Strain in Chicken Embryonic Fibroblasts

Viruses, 2020
Marek’s disease is a major scourge challenging poultry health worldwide. It is caused by the highly contagious Marek’s disease virus (MDV), an alphaherpesvirus.
Yashar Sadigh, Abdessamad Tahiri-Alaoui, Stephen Spatz, Venugopal Nair, Paolo Ribeca   +4 more
doaj   +1 more source