Results 41 to 50 of about 518 (147)

The Emergence of a vv + MDV Can Break through the Protections Provided by the Current Vaccines

Viruses, 2020
Marek’s disease (MD) is an infectious malignant T-cell lymphoma proliferative disease caused by Marek’s disease virus (MDV). In recent years, the emergence of very virulent (vv) and/or very virulent plus (vv +) strains of MDV in the field has been ...
Meng-ya Shi, Min Li, Wei-wei Wang, Qiao-mu Deng, Qiu-hong Li, Yan-li Gao, Pei-kun Wang, Teng Huang, Ping Wei   +8 more
doaj   +1 more source

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus

Poultry Science, 2020
SC9-2 is a recombinant Marek's disease virus (MDV) strain lacking the meq oncogene. Previous study demonstrated that SC9-2 virus provides good protection against challenge with a very virulent MDV rMd5, but it induces immunosuppressive effects in ...
Peng Sun, Ning Cui, Linqing Liu, Shuai Su, Ziqiang Cheng, Ruiai Chen, Yanpeng Li, Zhizhong Cui   +7 more
doaj   +1 more source

Probable congenital transmission of reticuloendotheliosis virus caused by vaccination with contaminated vaccines. [PDF]

PLoS ONE, 2012
Contaminated vaccine is one unexpected and potential origin of virus infection. In order to investigate the most likely cause of disease in a broiler breeder company of Shandong Province, all 17 batches of live-virus vaccines used in the affected flocks ...
Kai Wei, Zhenhong Sun, Shufen Zhu, Wenlong Guo, Pengcheng Sheng, Zunmin Wang, Changliang Zhao, Qingyou Zhao, Ruiliang Zhu   +8 more
doaj   +1 more source

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Viruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Jumpei Sato, Shiro Murata, Zhiyuan Yang, Benedikt B. Kaufer, Sotaro Fujisawa, Hikari Seo, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Nikolaus Osterrieder, Mark S. Parcells, Kazuhiko Ohashi   +11 more
doaj   +1 more source

Pathogenicity of a Very Virulent Strain of Marek′s Disease Herpesvirus Cloned as Infectious Bacterial Artificial Chromosomes

BioMed Research International, Volume 2011, Issue 1, 2011., 2011
Bacterial artificial chromosome (BAC) vectors containing the full‐length genomes of several herpesviruses have been used widely as tools to enable functional studies of viral genes. Marek′s disease viruses (MDVs) are highly oncogenic alphaherpesviruses that induce rapid‐onset T‐cell lymphomas in chickens. Oncogenic strains of MDV reconstituted from BAC
Lorraine P. Smith, Lawrence J. Petherbridge, Susan J. Baigent, Jennifer Simpson, Venugopal Nair, Gregory Tannock   +5 more
wiley   +1 more source

A Novel Effective and Safe Vaccine for Prevention of Marek’s Disease Caused by Infection with a Very Virulent Plus (vv+) Marek’s Disease Virus

Vaccines, 2021
Marek’s disease virus (MDV) is a highly contagious alphaherpesvirus that causes rapid onset lymphoma in chickens. Marek’s disease (MD) is effectively controlled using vaccination; however, MDV continues to break through vaccinal immunity, due to the ...
Yifei Liao, Sanjay M. Reddy, Owais A. Khan, Aijun Sun, Blanca Lupiani   +4 more
doaj   +1 more source

Development of novel virus vectors for influenza vaccination [PDF]

, 2012
The influenza virus, a member of the Orthomyxoviridae family, causes regular, large-scale morbidity and mortality in birds and humans and significant human suffering and economic loss.
Wasson, Peter Stewart
core   +4 more sources

Characterization of the Meq oncoproteins of Marek's disease virus vaccine strain CVI988/Rispens [PDF]

, 2009
Marek?s disease virus serotype-1 (MDV-1) causes T cell lymphomas in chickens. Vaccines prepared from attenuated CVI988/Rispens MDV-1 strain currently offer the best protection.
Ajithdoss, Dharani K.
core   +1 more source

Molecular characterisation and phylogenetic analysis of Marek's disease virus in Turkish layer chickens

, 2021
1. There is no current data about the genotypes of Marek's disease virus (MDV) in Turkish poultry flocks; hence, this study was performed to analyse CVI988/Rispens, turkey herpesvirus (HVT) vaccine viruses and MDV field viruses as well as to perform ...
YILMAZ, Aysun, Bayraktar, E., Umar, S., Cakan, B., Yilmaz, H., Tali, H. E., Aydin, O., Baigent, S., Sadeyen, J-R, Iqbal, M., Nair, V, Turan, N.   +11 more
core   +1 more source

Safety and Efficacy Evaluation of Recombinant Marek’s Disease Virus with REV-LTR

Vaccines, 2020
Recently, chickens vaccinated with the CVI988/Rispens vaccine showed increased tumor incidence. Moreover, many strains of Marek’s disease virus (MDV) that were naturally integrated with the long terminal repeat (LTR) of the avian reticuloendotheliosis ...
Cuiping Song, Yang Yang, Jing Hu, Shengqing Yu, Yingjie Sun, Xvsheng Qiu, Lei Tan, Chunchun Meng, Ying Liao, Weiwei Liu, Chan Ding   +10 more
doaj   +1 more source