Results 21 to 30 of about 354 (118)

Development of an ELISPOT assay for numerating IFN-γ-secreting T cells in chicken using novel monoclonal antibodies [PDF]

Poultry Science
Cellular immune responses play critical roles in the control of pathogenic infection. The measurement of antigen-specific IFN-γ-secreting T cells via an enzyme-linked immunospot assay (ELISPOT) is a valuable method for the evaluation of cellular immune ...
Zhou Zhou, Ji Wu, Huining Zhang, Xinjie Yuan, Ye Meng, Lina Chen, Yi Yang, Xiaoli Hao, Shaobin Shang   +8 more
doaj   +2 more sources

A Review on the Marek’s Disease Outbreak and Its Virulence-Related meq Genovariation in Asia between 2011 and 2021 [PDF]

Animals, 2022
Marek’s disease is an infectious disease in poultry that usually appears in neural and visceral tumors. This disease is caused by Gallid alphaherpesvirus 2 infection in lymphocytes, and its meq gene is commonly used in virulent studies for coding the key
Baolin Song, Jehan Zeb, Sabir Hussain, Muhammad Umair Aziz, Elena Circella, Gaia Casalino, Antonio Camarda, Guan Yang, Nicolas Buchon, Olivier Sparagano   +9 more
doaj   +2 more sources

Surveillance and Molecular Characterization of Marek’s Disease Virus (MDV) Strains Circulating in Tanzania [PDF]

Viruses
Marek’s disease (MD) is a highly contagious and oncogenic viral disease of poultry, causing significant economic losses due to mortality and reduced performance. The rapid evolution of Marek’s disease virus (MDV) has been reported in poultry farms, often
Augustino Alfred Chengula, Herbertha Mpete, Ramadhani Juma Makasali   +2 more
doaj   +2 more sources

Marek’s Disease Virus (MDV) Meq Oncoprotein Plays Distinct Roles in Tumor Incidence, Distribution, and Size [PDF]

Viruses
Marek’s disease (MD), characterized by the rapid onset of T-cell lymphomas in chickens, is caused by Mardivirus gallidalpha2, an oncogenic alphaherpesvirus commonly known as Marek’s disease virus (MDV).
Dharani K. Ajithdoss, Yifei Liao, Sanjay M. Reddy, Blanca Lupiani   +3 more
doaj   +2 more sources

Circulating hypervirulent Marek's disease viruses in vaccinated chicken flocks in Taiwan by genetic analysis of meq oncogene. [PDF]

PLoS ONE
Marek's disease (MD) is an important neoplastic disease caused by serotype 1 Marek's disease virus (MDV-1), which results in severe economic losses worldwide.
Ming-Chu Cheng, Guan-Hua Lai, Yi-Lun Tsai, Yi-Yang Lien   +3 more
doaj   +2 more sources

Epigenetic Factor MicroRNAs Likely Mediate Vaccine Protection Efficacy against Lymphomas in Response to Tumor Virus Infection in Chickens through Target Gene Involved Signaling Pathways [PDF]

Veterinary Sciences
Epigenetic factors, including microRNAs (miRNAs), play an important role in affecting gene expression and, therefore, are involved in various biological processes including immunity protection against tumors.
Lei Zhang, Qingmei Xie, Shuang Chang, Yongxing Ai, Kunzhe Dong, Huanmin Zhang   +5 more
doaj   +2 more sources

Marek’s disease vaccines-induced differential expression of known and novel microRNAs in primary lymphoid organ bursae of White Leghorn

Veterinary Research, 2020
Marek’s disease (MD) is a contagious disease of domestic chickens caused by MD viruses. MD has been controlled primarily by vaccinations, yet sporadic outbreaks of MD take place worldwide.
Lei Zhang, Chen Zhu, Mohammad Heidari, Kunzhe Dong, Shuang Chang, Qingmei Xie, Huanmin Zhang   +6 more
doaj   +1 more source

Transcriptional Profiles Associated with Marek’s Disease Virus in Bursa and Spleen Lymphocytes Reveal Contrasting Immune Responses during Early Cytolytic Infection

Viruses, 2020
Marek’s disease virus (MDV), an alpha herpes virus, causes a lymphoproliferative state in chickens known as Marek’s disease (MD), resulting in severe monetary losses to the poultry industry.
Huan Jin, Zimeng Kong, Arslan Mehboob, Bo Jiang, Jian Xu, Yunhong Cai, Wenxiao Liu, Jiabing Hong, Yongqing Li   +8 more
doaj   +1 more source

Induction of lymphomas by inoculation of Marek's disease virus-derived lymphoblastoid cell lines: prevention by CVI988 vaccination [PDF]

Avian Pathology, 2012
Lymphoblastoid cell lines 265(L) and 990(O) are monoclonal lymphomas, derived respectively from liver and ovarian tumours, generated in inbred P-line (MHC B(19)/B(19)) chickens infected with RB-1B strain of Marek's disease virus (MDV) and pRB-1B5 BAC clone respectively. These were inoculated into inbred, MDV-susceptible, P-line chickens by intra-venous
Mwangi, W, Smith, L, Baigent, S, Smith, A, Nair, V   +4 more
openaire   +3 more sources

Depression of Vaccinal Immunity to Marek’s Disease by Infection with Chicken Infectious Anemia Virus

Frontiers in Microbiology, 2017
Marek’s disease (MD) has been occurring with increasing frequency in chickens in recent years. To our knowledge, however, there has been no report of the very virulent plus (vv+) MD virus (MDV) field isolate in China.
Yankun Zhang, Yankun Zhang, Yankun Zhang, Ning Cui, Ning Cui, Ning Cui, Ning Cui, Ni Han, Ni Han, Ni Han, Jiayan Wu, Jiayan Wu, Jiayan Wu, Zhizhong Cui, Shuai Su, Shuai Su, Shuai Su   +16 more
doaj   +1 more source