Results 31 to 40 of about 354 (118)

Natural outbreak of Marek’s disease in indigenous chicken and Japanese quail (Coturnix coturnix japonica) in Jos, Plateau State, Nigeria [PDF]

open access: yesOpen Veterinary Journal, 2019
Carcasses of an indigenous adult chicken and Japanese quail from different flocks were presented to a veterinary clinic for postmortem (PM) examination in 2014 in Jos, Plateau State, Nigeria.
Adeyinka Jeremy Adedeji   +3 more
doaj   +1 more source

Marek’s Disease Virus Infection of Natural Killer Cells

open access: yesMicroorganisms, 2019
Natural killer (NK) cells are key players in the innate immune response. They kill virus-infected cells and are crucial for the induction of adaptive immune responses. Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that causes deadly
Luca D. Bertzbach   +4 more
doaj   +1 more source

The Emergence of a vv + MDV Can Break through the Protections Provided by the Current Vaccines

open access: yesViruses, 2020
Marek’s disease (MD) is an infectious malignant T-cell lymphoma proliferative disease caused by Marek’s disease virus (MDV). In recent years, the emergence of very virulent (vv) and/or very virulent plus (vv +) strains of MDV in the field has been ...
Meng-ya Shi   +8 more
doaj   +1 more source

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus

open access: yesPoultry Science, 2020
SC9-2 is a recombinant Marek's disease virus (MDV) strain lacking the meq oncogene. Previous study demonstrated that SC9-2 virus provides good protection against challenge with a very virulent MDV rMd5, but it induces immunosuppressive effects in ...
Peng Sun   +7 more
doaj   +1 more source

Probable congenital transmission of reticuloendotheliosis virus caused by vaccination with contaminated vaccines. [PDF]

open access: yesPLoS ONE, 2012
Contaminated vaccine is one unexpected and potential origin of virus infection. In order to investigate the most likely cause of disease in a broiler breeder company of Shandong Province, all 17 batches of live-virus vaccines used in the affected flocks ...
Kai Wei   +8 more
doaj   +1 more source

Pathogenicity of a Very Virulent Strain of Marek′s Disease Herpesvirus Cloned as Infectious Bacterial Artificial Chromosomes

open access: yesBioMed Research International, Volume 2011, Issue 1, 2011., 2011
Bacterial artificial chromosome (BAC) vectors containing the full‐length genomes of several herpesviruses have been used widely as tools to enable functional studies of viral genes. Marek′s disease viruses (MDVs) are highly oncogenic alphaherpesviruses that induce rapid‐onset T‐cell lymphomas in chickens. Oncogenic strains of MDV reconstituted from BAC
Lorraine P. Smith   +5 more
wiley   +1 more source

Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

open access: yesViruses, 2022
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades.
Jumpei Sato   +11 more
doaj   +1 more source

A Chinese Variant Marek’s Disease Virus Strain with Divergence between Virulence and Vaccine Resistance

open access: yesViruses, 2017
Marek’s disease (MD) virus (MDV) has been evolving continuously, leading to increasing vaccination failure. Here, the MDV field strain BS/15 was isolated from a severely diseased Chinese chicken flock previously vaccinated with CVI988.
Guo-rong Sun   +12 more
doaj   +1 more source

Protection provided by Rispens CVI988 vaccine against Marek's disease virus isolates of different pathotypes and early prediction of vaccine take and MD outcome [PDF]

open access: yesAvian Pathology, 2016
We tested the level of protection provided by the Rispens CVI988 (Rispens) vaccine against challenge with a virulent Marek's disease virus (MDV) pathotype (vMDV) and a very virulent pathotype (vvMDV) and the accuracy of a range of predictive measures of Marek's disease (MD) incidence and vaccine take.
Sithara, Ralapanawe   +3 more
openaire   +2 more sources

The construction and characterization of the bi-directional promoter between pp38 gene and 1.8-kb mRNA transcripts of Marek's disease viruses

open access: yesVirology Journal, 2009
Background Marek's disease virus (MDV) has a bi-directional promoter between pp38 gene and 1.8-kb mRNA transcripts. By sequencing for the promoters from 8 different strains (CVI988, 814, GA, JM, Md5, G2, RB1B and 648A), it is found, comparing with the ...
Ding Jiabo, Chen Ruiai, Wang Bin
doaj   +1 more source

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