Results 31 to 40 of about 518 (147)

Protection conferred by a recombinant Marek’s disease virus that expresses the spike protein from infectious bronchitis virus in specific pathogen-free chicken [PDF]

Virology Journal, 2012
Background In many countries, the predominant field isolates of infectious bronchitis virus (IBV) have been classified as QX-like strains since 1996.
Zhang Xiaorong, Wu Yantao, Huang Yezhen, Liu Xiufan   +3 more
doaj   +2 more sources

Marek’s Disease Virus (MDV) Meq Oncoprotein Plays Distinct Roles in Tumor Incidence, Distribution, and Size [PDF]

Viruses
Marek’s disease (MD), characterized by the rapid onset of T-cell lymphomas in chickens, is caused by Mardivirus gallidalpha2, an oncogenic alphaherpesvirus commonly known as Marek’s disease virus (MDV).
Dharani K. Ajithdoss, Yifei Liao, Sanjay M. Reddy, Blanca Lupiani   +3 more
doaj   +2 more sources

Circulating hypervirulent Marek's disease viruses in vaccinated chicken flocks in Taiwan by genetic analysis of meq oncogene. [PDF]

PLoS ONE
Marek's disease (MD) is an important neoplastic disease caused by serotype 1 Marek's disease virus (MDV-1), which results in severe economic losses worldwide.
Ming-Chu Cheng, Guan-Hua Lai, Yi-Lun Tsai, Yi-Yang Lien   +3 more
doaj   +2 more sources

Epigenetic Factor MicroRNAs Likely Mediate Vaccine Protection Efficacy against Lymphomas in Response to Tumor Virus Infection in Chickens through Target Gene Involved Signaling Pathways [PDF]

Veterinary Sciences
Epigenetic factors, including microRNAs (miRNAs), play an important role in affecting gene expression and, therefore, are involved in various biological processes including immunity protection against tumors.
Lei Zhang, Qingmei Xie, Shuang Chang, Yongxing Ai, Kunzhe Dong, Huanmin Zhang   +5 more
doaj   +2 more sources

An Anti-Tumor Vaccine Against Marek's Disease Virus Induces Differential Activation and Memory Response of γδ T Cells and CD8 T Cells in Chickens

Frontiers in Immunology, 2021
Marek's disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes deadly T-cell lymphomas and serves as a natural virus-induced tumor model in chickens.
Xiaoli Hao, Xiaoli Hao, Xiaoli Hao, Shuai Li, Jiaqi Li, Yi Yang, Yi Yang, Yi Yang, Aijian Qin, Aijian Qin, Aijian Qin, Aijian Qin, Shaobin Shang, Shaobin Shang, Shaobin Shang, Shaobin Shang   +15 more
doaj   +1 more source

Genetic evolution of Marek's disease virus in vaccinated poultry farms [PDF]

Veterinary World, 2021
Background and Aim: The Marek's disease virus (MDV) is a neoplastic disease causing serious economic losses in poultry production. This study aimed to investigate MDV occurrence in poultry flocks in the Lower Egypt during the 2020 breakout and ...
Nahed Yehia, Hemat S. El-Sayed, Sabry E. Omar, Ahmed Erfan, Fatma Amer   +4 more
doaj   +1 more source

Marek’s disease vaccines-induced differential expression of known and novel microRNAs in primary lymphoid organ bursae of White Leghorn

Veterinary Research, 2020
Marek’s disease (MD) is a contagious disease of domestic chickens caused by MD viruses. MD has been controlled primarily by vaccinations, yet sporadic outbreaks of MD take place worldwide.
Lei Zhang, Chen Zhu, Mohammad Heidari, Kunzhe Dong, Shuang Chang, Qingmei Xie, Huanmin Zhang   +6 more
doaj   +1 more source

Deletion of the Viral Thymidine Kinase in a Meq-Deleted Recombinant Marek’s Disease Virus Reduces Lymphoid Atrophy but Is Less Protective

Microorganisms, 2021
Marek’s disease (MD) is a ubiquitous disease of domesticated chickens and its etiologic agent is the Gallid alphaherpesvirus 2 (GaHV-2), also known as Marek’s disease virus (MDV). MD is currently controlled by vaccination using live attenuated strains of
Steven J. Conrad, Eniope B. Oluwayinka, Mohammad Heidari, Jody K. Mays, John R. Dunn   +4 more
doaj   +1 more source

Natural outbreak of Marek’s disease in indigenous chicken and Japanese quail (Coturnix coturnix japonica) in Jos, Plateau State, Nigeria [PDF]

Open Veterinary Journal, 2019
Carcasses of an indigenous adult chicken and Japanese quail from different flocks were presented to a veterinary clinic for postmortem (PM) examination in 2014 in Jos, Plateau State, Nigeria.
Adeyinka Jeremy Adedeji, Olatunde Babatunde Akanbi, Pam Dachung Luka, Paul Abdu   +3 more
doaj   +1 more source

Marek’s Disease Virus Infection of Natural Killer Cells

Microorganisms, 2019
Natural killer (NK) cells are key players in the innate immune response. They kill virus-infected cells and are crucial for the induction of adaptive immune responses. Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that causes deadly
Luca D. Bertzbach, Daphne A. van Haarlem, Sonja Härtle, Benedikt B. Kaufer, Christine A. Jansen   +4 more
doaj   +1 more source