Results 81 to 90 of about 7,578 (214)

Table_1_A Computational Pipeline for the Diagnosis of CVID Patients.DOCX [PDF]

, 2019
Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub)classes and/or impaired antibody responses caused by
Sofie Van Gassen (7329173), Melissa Dullaers (119505), Annelies Emmaneel (7329170), Filomeen Haerynck (5913119), Simon J. Tavernier (5913104), Delfien J. Bogaert (5913098), Yvan Saeys (3781)   +6 more
core   +1 more source

Involvement of miR-142 and miR-155 in Non-Infectious Complications of CVID [PDF]

, 2020
Background and objectives: Common variable immunodeficiency (CVID) is the most prevalent antibody impairment. It is characterized by failure in immunoglobulin and protective antibody generation and defined by an increased tendency toward bacterial ...
Federica Vita, Sebastiano Gangemi, Giovanni Pioggia, Paola Lucia Minciullo, Paolina Quattrocchi, Giuliana Amato   +5 more
core   +1 more source

Common Variable Immunodeficiency (CVID)

Journal of Clinical Review & Case Reports, 2018
Common Variable Immunodeficiency (CVID) refers to a heterogeneous group of primary immune deficiency disorders (PIDD) presenting with recurrent sinopulmonary infections, hypogammagloblunemia, inadequate vaccination responses, and in a subset, co-existent autoimmune and inflammatory disease.
Suzahn Ebert, Sonali Bracken, John Woosley, Kevin G. Greene, Jonathan Hansen, Leonard Jason Lobo, Teresa Kathleen Tarrant   +6 more
openaire   +2 more sources

Monitoring patients with uncomplicated common variable immunodeficiency: a systematic review

Allergy, Asthma & Clinical Immunology, 2022
Background Non-infectious complications have become a major cause of morbidity and mortality in patients with Common Variable Immunodeficiency (CVID). The monitoring of patients with CVID prior to the development of non-infectious complications is not ...
Erika Yue Lee, Stephen Betschel, Eyal Grunebaum   +2 more
doaj   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, Volume 9, Issue 5, Page 898-913, May 2026.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Association of serum copeptin levels with pulmonary complications and heart right ventricular functions in common variable immunodeficiency

BMC Immunology
Background and aims Common variable immunodeficiency (CVID) represents the most frequently diagnosed symptomatic primary immunodeficiency (PID), marked by a heterogeneous presentation involving infectious and non-infectious symptoms.
Mehmet Kılınç, Fatih Çölkesen, Filiz Sadi Aykan, Recep Evcen, Eray Yıldız, Bahadır Feyzioğlu, Metin Doğan, Yakup Alsancak, Sefa Tatar, Şevket Arslan   +9 more
doaj   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang, Hui Jing, Yuhan Chen, Ling Zhong, Jiyun Yang   +4 more
wiley   +1 more source

Increased expression of inhibitory receptors on CD4 T cells in CVID. [PDF]

, 2013
(A) Levels of PD-1 expressed in CD4 T cells in healthy controls and CVID patients (left panel), and in CVID patients before and after IVIg treatment (right panel).
Jorge Kalil (52916), Markus Moll (109640), Cristina M. Kokron (468576), Dominic Paquin-Proulx (468572), Bianca A. N. Santos (468573), Karina I. Carvalho (244966), Ana Karolina Barreto de Oliveira (468575), Johan K. Sandberg (353026), Myrthes Toledo-Barros (468574), Esper G. Kallas (36139)   +9 more
core   +1 more source

Functional Defects in the NFκB pathway in Common Variable Immunodeficiency

Journal of Human Immunity
Common variable Immunodeficiency (CVID) is a heterogeneous immunodeficiency characterized by hypogammaglobulinemia and immune dysregulation. In up to 30% of cases, there is a monogenic defect, with a fraction of these familial. The majority, however, are
Terrence T.J. Hunter, Ioasaf Karafotias, David Fear, Mark Peakman, Mohammad A.A. Ibrahim   +4 more
doaj   +1 more source

Double‐Blind Placebo Challenge Confirmation of Diphenhydramine Allergy

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Diphenhydramine, a first‐generation H1–antihistamine commonly used for allergic symptom relief and infusion premedication, rarely causes true systemic hypersensitivity. When suspected reactions are mild and subjective—particularly in anxious patients—objective confirmation is essential.
Ruchi Patel, Aleena Mahmood, Eugenio Capitle   +2 more
wiley   +1 more source