Results 71 to 80 of about 7,578 (214)
Cellular immunity in COVID-19 and other infections in Common variable immunodeficiency
COVID-19 has shed light on the role of cellular immunity in the absence of humoral response in different patient groups. Common variable immunodeficiency (CVID) is characterized by impaired humoral immunity but also an underlying T-cell dysregulation ...
Ragnhild Øye Løken +2 more
doaj +1 more source
Good Syndrome Presenting With Pulmonary Abnormalities Four Years After Thymectomy
Good syndrome may become clinically apparent several years after thymectomy and can present with pulmonary abnormalities. In this case, ground‐glass opacities and BAL lymphocytosis suggested possible inflammatory features, although infection could not be excluded.
Tomohide Hanawa +7 more
wiley +1 more source
Image_3_A Computational Pipeline for the Diagnosis of CVID Patients.PNG [PDF]
Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub)classes and/or impaired antibody responses caused by
Sofie Van Gassen (7329173) +6 more
core +1 more source
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng +6 more
wiley +1 more source
Analysis of families with common variable immunodeficiency (CVID) and IgA deficiency suggests linkage of CVID to chromosome 16q [PDF]
Common variable immunodeficiency (CVID) is an antibody deficiency syndrome that often co-occurs in families with selective IgA deficiency (IgAD). Vorechovský et al. (Am J Hum Genet 64:1096-1109, 1999; J Immunol 164:4408-4416, 2000) ascertained and genotyped 101 multiplex IgAD families and used them to identify and fine map the IGAD1 locus on chromosome
SCHAFFER AA +5 more
openaire +4 more sources
Image_2_A Computational Pipeline for the Diagnosis of CVID Patients.PNG [PDF]
Common variable immunodeficiency (CVID) is one of the most frequently diagnosed primary antibody deficiencies (PADs), a group of disorders characterized by a decrease in one or more immunoglobulin (sub)classes and/or impaired antibody responses caused by
Sofie Van Gassen (7329173) +6 more
core +1 more source
A substantial proportion of patients with common variable immunodeficiency (CVID) have inflammatory and autoimmune complications of unknown etiology.
Magnhild E. Macpherson +38 more
doaj +1 more source
Altered expression of co-stimulatory molecules on mDCs in CVID. [PDF]
(A) Representative staining illustrating the gating strategy used. (B) Frequency of mDCs in blood from healthy controls and CVID patients (left panel), and in CVID patients before and after IVIg treatment (right panel). Comparison of the MFI of CD40 (C),
Jorge Kalil (52916) +9 more
core +1 more source
IL-10-Producing Regulatory B Cells Are Decreased in Patients with Common Variable Immunodeficiency. [PDF]
Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency in adults. CVID patients often present changes in the frequency and function of B lymphocytes, reduced number of Treg cells, chronic immune activation ...
Nathalia Silveira Barsotti +5 more
doaj +1 more source
This graphical abstract demonstrates a “rare‐to‐common” translational pipeline. Insights from rare monogenic conditions reveal key mechanisms of immune dysregulation. This knowledge informs the understanding of polygenic common allergic diseases, which share overlapping pathogenic pathways.
Riccardo Castagnoli +26 more
wiley +1 more source

