Results 91 to 100 of about 17,635 (197)

CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease

Journal of Neuroinflammation, 2011
Background Parkinson's disease is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. The cause of the neurodegeneration is unknown.
Hudson Charles E, Bachstetter Adam D, Pabon Mibel M, Gemma Carmelina, Bickford Paula C   +4 more
doaj   +1 more source

Effects of CX3CL1 inhibition on murine bleomycin-induced interstitial pneumonia

European Journal of Inflammation, 2020
Background: Treatment for interstitial pneumonia (IP) associated with collagen diseases has not been established. There is a need to elucidate the pathogenesis of IP and develop a novel therapy.
Soichi Yamada, Shion Miyoshi, Junko Nishio, Satoshi Mizutani, Zento Yamada, Natsuko Kusunoki, Hiroshi Sato, Yoshikazu Kuboi, Kana Hoshino-Negishi, Naoto Ishii, Toshio Imai, Tetsuo Mikami, Hiroyasu Nakano, Shinichi Kawai, Toshihiro Nanki   +14 more
doaj   +1 more source

The role of the CX3CL1/CX3CR1 axis as potential inflammatory biomarkers in subjects with periodontitis and rheumatoid arthritis: A systematic review

Immunity, Inflammation and Disease
This systematic review aimed to investigate the role of the C‐X3‐C motif ligand 1/chemokine receptor 1 C‐X3‐C motif (CX3CL1/CX3CR1) axis in the pathogenesis of periodontitis.
M. A. Alarcón-Sánchez, J. Becerra-Ruiz, Celia Guerrero-Velázquez, S. A. Mosaddad, A. Heboyan   +4 more
semanticscholar   +1 more source

Circulating Myokine Responses to Acute Endurance Exercise and Their Role in Immunoregulation: A Systematic Review and Meta‐Analysis

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
This systematic review and meta‐analysis, which examined the effects of acute endurance training on immunoregulatory myokines, showed significant small‐moderate to very large positive effect sizes for IL‐6, IL‐10, IL‐1ra, IL‐8, IL‐15, and TNF‐α. These effects were significantly moderated by risk of bias, sex, age, V̇O2peak, experience, type of exercise,
Miriam Ringleb, Fabian Fabritius, Jakob Godde, Christian Puta, Wilhelm Bloch, Florian Javelle   +5 more
wiley   +1 more source

Decision letter for "Ursodeoxycholic acid impairs liver‐infiltrating T cell chemotaxis through IFNγ and CX3CL1 production in primary biliary cholangitis"

, 2021

openalex   +1 more source

Exploration of C-terminal CX3CL1 for reducing age-dependent neurodegeneration

, 2023
Jacob Hudobenko, Manoshi Gayen, Marc Benoit, Neeraj Kumar Singh, Riqiang Yan   +4 more
openalex   +1 more source

Polyphyllin VII promotes hepatic stellate cell ferroptosis via the HIC1/CX3CL1/GPX4 axis

Journal of Pharmaceutical Analysis
Ferroptosis has been shown to mediate the development of fibrosis. Polyphyllin VII (PP7), a bioactive component of Paris polyphylla, exhibits potent anti-inflammatory activity and can significantly alleviate liver fibrosis.
Feng Jiang, Xinmiao Li, Mengyuan Li, Weizhi Zhang, Yifei Li, Lifan Lin, Lu He, Jianjian Zheng   +7 more
semanticscholar   +1 more source

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses [PDF]

, 2001
Paolo Fraticelli, Marina Sironi, Giuseppe Bianchi, Daniele D’Ambrosio, Cristina Albanesi, Antonella Stoppacciaro, Marcello Chieppa, Paola Allavena, Luigi P. Ruco, Giampiero Girolomoni, Francesco Sinigaglia, Annunciata Vecchi, Alberto Mantovani   +12 more
openalex   +1 more source

ATP secreted by endothelial cells blocks CX3CL1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y11 receptor activation [PDF]

, 2010
Stefania Gorini, G Callegari, Giulia Romagnoli, Caterina Mammi, Domenico Mavilio, Giuseppe Rosano, Massimo Fini, Francesco Di Virgilio, Sara Gulinelli, Simonetta Falzoni, Andrea Cavani, Davide Ferrari, Andrea Sala   +12 more
openalex   +1 more source

Fractalkine Modulates Microglia Metabolism in Brain Ischemia

Frontiers in Cellular Neuroscience, 2019
In the CNS, the chemokine CX3CL1 (fractalkine) is expressed on neurons while its specific receptor CX3CR1 is expressed on microglia and macrophages.
Clotilde Lauro, Giuseppina Chece, Lucia Monaco, Fabrizio Antonangeli, Giovanna Peruzzi, Serena Rinaldo, Alessio Paone, Francesca Cutruzzolà, Cristina Limatola, Cristina Limatola   +9 more
doaj   +1 more source