Results 81 to 90 of about 17,635 (197)
Clinical Chemistry and Laboratory MedicineObjectives The objective of our study was to evaluate serum CX3CL1/Fractalkine, a monocyte/macrophage chemoattractant expressed in cytotrophoblasts and decidual cells, as a predictive biomarker for the occurrence of preterm premature rupture of membranes
Samy Kahouadji +11 more
semanticscholar +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Emerging evidence highlights the central role of peripheral immune–metabolic regulation in the pathogenesis of Alzheimer's disease and related dementias (ADRD). Among peripheral organs, the spleen has gained increasing attention as a critical immune–metabolic hub linking systemic homeostasis to central neurodegeneration.
Jingsi Yan +7 more
wiley +1 more source
Chemokine CX3CL1 (Fractalkine) Signaling and Diabetic Encephalopathy
International Journal of Molecular SciencesDiabetes mellitus (DM) is the most common metabolic disease in humans, and its prevalence is increasing worldwide in parallel with the obesity pandemic.
M. Wątroba +2 more
semanticscholar +1 more source
Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications
MedComm – Oncology, Volume 5, Issue 1, March 2026.Cellular senescence shapes tumor progression through both antitumor and protumor mechanisms. Senescence triggered by telomere shortening restricts malignant transformation and limits tumor cell proliferation, while the senescence‐associated secretory phenotype (SASP) secretion enhances antitumor immunity by activating cytotoxic T cells.
Huajie Mao +5 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 5, Page 990-1008, March 2026.Background and Purpose Inflammation plays a crucial role in the development and progression of numerous acute and chronic diseases such as myocardial infarction (MI) and heart failure. Targeting ADAM proteases, particularly ADAM10, holds promise for fine‐tuning inflammatory responses.
Erik Klapproth +16 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2014 Background/Aims: During the resolution phase of inflammation, release of “find-me” signals by apoptotic cells is crucial in the chemoattraction of macrophages toward apoptotic cells for subsequent phagocytosis, in which microparticles derived from ...
Wen-Hui Tsai +6 more
doaj +1 more source
A Transcriptomic Analysis of Cancer‐Stromal Interactome in Lung Cancer Xenograft Models
Cancer Science, Volume 117, Issue 3, Page 841-851, March 2026.We conducted a comprehensive analysis of the lung cancer interactome to identify key ligand–receptor pairs involved in the aggressiveness of lung adenocarcinoma. Tumor necrosis factor superfamily member 12 and its receptor tumor necrosis factor receptor superfamily member 12A signaling axis may be potential candidates for therapeutic intervention for ...
Yuriko Takayama‐Isagawa +16 more
wiley +1 more source
Mediators of Inflammation, 2013 Chemokine CX3CL1 is unique, possessing the ability to act as a dual agent: chemoattractant and adhesive compound. Acting via its sole receptor CX3CR1, CX3CL1 participates in many processes in human placental tissue, including inflammation and ...
Dariusz Szukiewicz +5 more
doaj +1 more source
Arthritis Research & TherapyBackground Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular injury and inflammation, followed by excessive fibrosis of the skin and other internal organs, including the lungs.
T. Hasegawa +12 more
semanticscholar +1 more source
Tui Na Acupressure Modulates Treg Immunosuppression via FoxP3/mTORC1 Signalling in ALS Mice
Immunology, Volume 177, Issue 3, Page 481-500, March 2026.The proposed mechanism by which Tui Na acupressure improves motor and cognitive dysfunction in ALS mice by activating the FoxP3/mTORC1 pathway. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease driven by neuroinflammation, where regulatory T cell (Treg) dysfunction exacerbates immune imbalance.
Jie Han +7 more
wiley +1 more source