Results 101 to 110 of about 7,042 (282)

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

Biomass burning and urban air pollution over the Central Mexican Plateau [PDF]

Atmospheric Chemistry and Physics, 2009
Observations during the 2006 dry season of highly elevated concentrations of cyanides in the atmosphere above Mexico City (MC) and the surrounding plains demonstrate that biomass burning (BB) significantly impacted air quality in the region.
P. O. Wennberg, R. J. Yokelson, A. J. Weinheimer, D. C. McCabe, L. K. Emmons, T. L. Campos, E. C. Apel, A. D. Clarke, D. R. Blake, P. F. DeCarlo, J. D. Crounse, J. L. Jimenez   +11 more
doaj  

Elastomeric Core‐Conductive Shell Slurry Additive Stabilizes High‐Voltage NCM811 Cathodes via Mechanical‐Electrical Dual Regulation

Advanced Science, EarlyView.
A core‐shell ASA slurry additive constructs a mosaic‐like interface on high‐voltage NCM811 cathodes. This architecture decouples interfacial functions: the elastomeric core buffers mechanical stress to prevent microcracking, while the conductive shell facilitates rapid ion/electron transport, enabling mechanical‐electrical dual regulation and enhanced ...
Jiamin Duan, Xingchen Liu, Jiapei Li, Zhuijun Xu, Said Amzil, Baohu Wu, Yiyao Xiao, Wenjun Zhang, Tong Yu, Xiaohong Li, Wenwen Xue, Xiangyu Chen, Changwei Liu, Jie Gao, Peter Müller‐Buschbaum, Ya‐Jun Cheng, Yonggao Xia   +16 more
wiley   +1 more source

Hydrogen Cyanide Formation on the Analysis of Total Cyanide and Free Cyanide and Improvements of Pretreatment Method of Total Cyanide

BUNSEKI KAGAKU, 2009
シアン化合物は有毒物質であることから，環境及び排水中の全シアンは厳しく規制されている．環境及び排水中の全シアンの分析は，工場排水試験方法（JIS K 0102）に基づいて行われているが，この方法で分析したとき，シアン化合物を使用していない工場及び事業所の排水や廃棄物から全シアンが検出される事例が多数報告されている．本稿では，著者らが既に報告したプリント基板めっき工場，ノーシアン亜鉛めっき工場，カラー写真処理廃液，現像所排水，熱硬化性塗料，アルミニウム合金溶融廃棄物からのシアン化水素（HCN）生成事例と，最近明らかになったアルカリ固定による室温でのシアン化物イオン生成，重油燃焼排ガス洗浄液及び石炭火力発電所排水からのHCN生成事例を紹介し，その生成原因について述べた．また ...
openaire   +2 more sources

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Poly (vinylpyrrolidone)-Grafted Silica as a Polymeric Cosolvent Catalyst for Organic Transformations in Organic and Aqueous Media [PDF]

Journal of Sciences, Islamic Republic of Iran, 2015
Poly (vinylpyrrolidone)-grafted silica as an organic-inorganic hybrid material was used as an effective heterogeneous polymeric cosolvent catalyst in organic reactions.
S. Ghasemi, B. Tamami, R. Teymoori, H. Allahyari   +3 more
doaj  

Cyanide antagonist [PDF]

Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 1981
C J, Vesey, P V, Cole
openaire   +2 more sources

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Highly (Z)-Selective Synthesis of β-Monosubstituted α,β-Unsaturated Cyanides Using the Peterson Reaction

, 2016
The Peterson reaction between (t-BuO)Ph2SiCH2CN and various aldehydes furnishes the corresponding β-monosubstituted α,β-unsaturated cyanides with high Z selectivity (Z:E = 92:8 to >98:2)
Atsushi Yamakawa (2704099), Tomohide Fukuzaki (2704102), Satoshi Kojima (1896265), Yutaka Murai (2704105)   +3 more
core   +2 more sources

The chemistry of 2,3-unsaturated glycosyl cyanides

, 1991
Carbohydrate research remains one of the most exciting endeavors in the field of organic chemistry. The importance of carbohydrates needs little elaboration.
Wei, YiQiu
core