Results 121 to 130 of about 40,160 (316)

Formation of water-soluble metal cyanide complexes from solid minerals by Pseudomonas plecoglossicida [PDF]

open access: yes, 2017
A few Pseudomonas species are able to form hydrocyanic acid (HCN), particularly when grown under glycine-rich conditions. In the presence of metals, cyanide can form water-soluble metal complexes of high chemical stability.
Brandl, Helmut, Faramarzi, Mohammad A.
core  

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

open access: yesAdvanced Theory and Simulations, EarlyView.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer   +7 more
wiley   +1 more source

THE IMPACT OF COAL WASTE HEAPS ON THE ENVIRONMENT OF SOKAL DISTRICT OF LVIV REGION [PDF]

open access: yes, 2018
The environmental situation in Sokal district is one of the most complicated in Lviv region, which is caused by man-made environmental impact of mining, coal preparation and chemical industries.
Popovych, Vasyl, Voloshchyshyn, Andriy
core  

Designing High Performance Organic Donor Molecules for Photovoltaics

open access: yesAdvanced Theory and Simulations, EarlyView.
Systematically tuning the fusion pattern and length of the π$\pi$‐bridge, along with adjusting the electron‐withdrawing (EW) strength of the terminal groups in small‐molecule donor A-π-Core-π$\text{A-}\pi \text{-Core-}\pi$‐A architectures, enables predictable modulation of the system's opto‐electronic properties.
Fabian Bauch   +2 more
wiley   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin   +15 more
wiley   +1 more source

SUSTAINABLE MANAGEMENT OF DOMESTIC WATER RESIDUES AND DIMINUTION OF DISCHARGES INTO MUNICIPAL COLLECTORS IN MEXICO [PDF]

open access: yes
This work is a study on the sustainable management of water according to the regulation and recommendations of sustainable architectural design of the environmental model by LEED® (Leadership in Energy and Environmental Design), particularly in respect ...
Martha CRÚZ-MEDINA, Silverio HERNÁNDEZ
core  

Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

open access: yesAdvanced Science, EarlyView.
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong   +5 more
wiley   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

open access: yesAdvanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou   +14 more
wiley   +1 more source

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