Results 51 to 60 of about 39,245 (323)

Cyanide at the origin of metabolism [PDF]

Nature Chemistry, 2022
The emergence of protometabolic reactions that evolved into today’s metabolic pathways is unclear. Now, evidence suggests that the chemical origin of biological carbon metabolism may have relied on the versatility of a single primitive C1 feedstock molecule — hydrogen cyanide.
openaire   +5 more sources

Osmotic pressure‐induced calcium response states

FEBS Open Bio, EarlyView.
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao, Keiji Naruse, Masatoshi Morimatsu   +2 more
wiley   +1 more source

Statutory, legal, scientific and productive aspects of conditions and prospects of development of antidote therapy in the Russian Federation

Вестник войск РХБ защиты, 2023
The modern period in the development of the world community and the Russian Federation in particular is characterized by the globalization of chemical danger.
V. D. Gladkikh, М. М. Muradov, N. А. Kolosova, I. К. Kasatkin, L. М. Slastilova   +4 more
doaj   +1 more source

The cometary composition of a protoplanetary disk as revealed by complex cyanides

, 2015
Observations of comets and asteroids show that the Solar Nebula that spawned our planetary system was rich in water and organic molecules. Bombardment brought these organics to the young Earth's surface, seeding its early chemistry.
A Dutrey, A Dutrey, C Brinch, C Favre, C Qi, C Qi, C Qi, C Walsh, C Walsh, C Walsh, C Walsh, Chunhua Qi, D Lynden-Bell, D Semenov, David J. Wilner, DM Graninger, DP O’Brien, E Bergin, E Dartois, E Herbst, EC Fayolle, EF van Dishoeck, EF van Dishoeck, EI Chiang, FJ Ciesla, GM Muñoz Caro, H Nomura, JS Carr, K Furuya, K Tsiganis, KA Rosenfeld, Karin I. Öberg, Kenji Furuya, KI Öberg, KI Öberg, KI Öberg, KJ Walsh, KM Pontoppidan, L Hartmann, LI Cleeves, LI Cleeves, M Dubernet, M Simon, M Takami, M Wernli, MJ Mumma, MP Collings, MR Hogerheijde, N Goldman, N Sakai, P D'Alessio, P Gratier, P Hartogh, RT Garrod, Ryan Loomis, S Guilloteau, S Pizzarello, Sean M. Andrews, T Yamamoto, V Piétu, V Wakelam, Viviana V. Guzmán, Y Aikawa, Y Aikawa, Yuri Aikawa   +64 more
core   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

A geometrical model for Mixed cyanide crystals

, 1999
A model of diluted random field sustained by quenched volume deformations is shown to reproduce puzzling physical features found in X(CN)_{x}Y_{1-x} mixed cyanide crystals. X is an alkali metal (K, Na or Rb) and Y is a spherical halogen ion (Br, Cl or I).
Aharony, Andelman, Binder, Galam, Galam, Galam, Galam, Galam, Galam, Henriques, Hessinger, Höchli, Kaufman, Knorr, Kwiecien, Loidl, Mattis, Serge Galam   +17 more
core   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

Copper–cobalt double metal cyanides as green catalysts for phosphoramidate synthesis

Communications Chemistry, 2023
Phosphoramidates are common and widespread backbones of a great variety of fine chemicals, pharmaceuticals, additives and natural products. Conventional approaches to their synthesis make use of toxic chlorinated reagents and intermediates, which are ...
Alejandro Fonseca, Aram L. Bugaev, Anna Yu. Pnevskaya, Kwinten Janssens, Carlos Marquez, Dirk De Vos   +5 more
doaj   +1 more source

Detection of a branched alkyl molecule in the interstellar medium: iso-propyl cyanide

, 2014
The largest non-cyclic molecules detected in the interstellar medium (ISM) are organic with a straight-chain carbon backbone. We report an interstellar detection of a branched alkyl molecule, iso-propyl cyanide (i-C3H7CN), with an abundance 0.4 times ...
Belloche, Arnaud, Garrod, Robin T., Menten, Karl M., Müller, Holger S. P.   +3 more
core   +1 more source

Spectroscopic investigation of the dynamical behavior of the photoinduced phase transition of Na0.6Co1.3[Fe(CN)6]∙4H2O [PDF]

, 2005
The dynamics of the photoinduced phase transition (PIPT) has been investigated for the Co-Fe cyanides film, Na0.6Co1.3[Fe(CN)6]∙4H2O , by means of the transient absorption spectroscopy.
Hashimoto K., Hozumi T., Moritomo Y., Nakamura A., Ohkoshi S., Yamauchi T., 守友 浩   +6 more
core   +1 more source