Results 51 to 60 of about 40,160 (316)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Copper–cobalt double metal cyanides as green catalysts for phosphoramidate synthesis

Communications Chemistry, 2023
Phosphoramidates are common and widespread backbones of a great variety of fine chemicals, pharmaceuticals, additives and natural products. Conventional approaches to their synthesis make use of toxic chlorinated reagents and intermediates, which are ...
Alejandro Fonseca, Aram L. Bugaev, Anna Yu. Pnevskaya, Kwinten Janssens, Carlos Marquez, Dirk De Vos   +5 more
doaj   +1 more source

Statutory, legal, scientific and productive aspects of conditions and prospects of development of antidote therapy in the Russian Federation

Вестник войск РХБ защиты, 2023
The modern period in the development of the world community and the Russian Federation in particular is characterized by the globalization of chemical danger.
V. D. Gladkikh, М. М. Muradov, N. А. Kolosova, I. К. Kasatkin, L. М. Slastilova   +4 more
doaj   +1 more source

Environmental risk assessments of uses cyanide in gold extraction on water quality parameters and its effect on rhodanese activities in selected organs of coptodon zillii in igun reservoir, Southwestern, Nigeria [PDF]

, 2022
Oluwakemi Victoria Okunola, Olaniyi Olusola Komolafe, Raphael Emuebie Okonji, Oluwadamilare Emmanuel Obayemi, Sakirat Temitope Asafa, Taiwo Adekanmi Adesakin   +5 more
openalex   +1 more source

Resonant inelastic x-ray scattering probes the electron-phonon coupling in the spin-liquid kappa-(BEDT-TTF)2Cu2(CN)3

, 2017
Resonant inelastic x-ray scattering at the N K edge reveals clearly resolved harmonics of the anion plane vibrations in the kappa-(BEDT-TTF)2Cu2(CN)3 spin-liquid insulator. Tuning the incoming light energy at the K edge of two distinct N sites permits to
Carniato, S., Foury-Leylekian, P., Ilakovac, V., Joly, Y., Kanoda, K., Lazic, P., Miyagawa, K., Nicolaou, A., Pouget, J. -P., Tomic, S.   +9 more
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

In situ measurements of HCN and CH3CN over the Pacific Ocean: Sources, sinks, and budgets [PDF]

, 2003
We report the first in situ measurements of hydrogen cyanide (HCN) and methyl cyanide (CH3CN, acetonitrile) from the Pacific troposphere (0-12 km) obtained during the NASA Transport and Chemical Evolution over the Pacific (TRACE-P) airborne mission ...
Blake, D, Czech, E, Fuelberg, H, Harward, CN, Herlth, D, Jacob, DJ, Kiley, CM, Kolyer, R, Kondo, Y, Li, Q, Sachse, G, Salas, L, Singh, HB, Viezee, W, Zhao, Y   +14 more
core  

Micropleated Nanofibrous Filters for High‐Efficiency Submicron Aerosol Filtration: A Comparative Study with Chemical, Biological, Radiological, and Nuclear Gas Mask Filters

Advanced Engineering Materials, EarlyView.
This study presents micropleated filters manufactured by needleless electrospinning. Nanofibers are deposited onto uniaxially pre‐stretched substrates that contract upon release, forming densely packed micropleats. This architecture increases effective surface area without enlarging the filter size, achieving quality factors comparable to those of ...
Aleksandr Fadeev, Kevin Crown, Sean Kinahan, Gabriel Lucero, Hayden Stromsodt, Svetlana Romanova, Yury Salkovskiy   +6 more
wiley   +1 more source

Cyanide poisoning after bitter almond ingestion: “A rare case report”

Clinical Case Reports
Key Clinical Message We present a case of a 36‐year‐old woman with a history of three suicide attempts who had ingested approximately 40 bitter almonds in a suicidal act, leading to her admission to the emergency department of a regional hospital due to ...
Neda Arabizadeh, Masoud Mahmoudi, Laaya Mokhtar Gandomani, Nastaran Eizadi‐Mood   +3 more
doaj   +1 more source

Toxic plants and companion animals. [PDF]

, 2009
Poisoning by substances of plant origin is unusual in both dogs and cats, yet it is possible; as many veterinarians do not know which plants can contain toxic active principles, the possibility of intoxication by ornamental plants commonly used to ...
SEVERINO, LORELLA
core   +1 more source