Results 31 to 40 of about 7,825 (219)

Cyanocobalamin improves memory impairment via inhibition of necrosis and apoptosis of hippocampal cell death after transient global ischemia/reperfusion [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): Brain ischemia/reperfusion (I/R) causes irreversible damage, particularly in the hippocampus. Cyanocobalamin (CNCbl) is known to be crucial for the proper operation of the nervous system.
Hossein Khastar, Behzad Garmabi, Fatemeh Zare Mehrjerdi, Mohamad Taghi Rahimi, Nabi Shamsaei, Amir-Hossein Ali, Nilofar Khorsand, Mehdi Khaksari   +7 more
doaj   +1 more source

A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans

FEBS Open Bio, 2014
In this study, we showed that cyanocobalamin dodecylamine, a ribose 5′-carbamate derivative of cyanocobalamin, was absorbed and accumulated to significant levels by Caenorhabditis elegans and was not further metabolized.
Tomohiro Bito, Yukinori Yabuta, Tsuyoshi Ichiyanagi, Tsuyoshi Kawano, Fumio Watanabe   +4 more
doaj   +1 more source

The prospects for the use of vitamin B12 derivatives in pharmacology

Фармакоэкономика, 2023
Background. The structure of corrin tetrapyrrole macrocycles (compounds similar in structure to vitamin B12) is a kind of universal chemical template for targeted drug delivery, and the development of chemical sensors and antidotes.Objective ...
I. Yu. Torshin, O. A. Gromova, L. A. Maiorova   +2 more
doaj   +1 more source

Microbiological method for determination of cyanocobalaminin in pharmaceutical formulation

Environment Conservation Journal, 2010
A simple and precise microbiological method has been developed for the quantitative estimation of Cyanocobalamin in pharmaceutical formulations. After employing different microorganisms for achieving best results, Escherichia coli 113-3 ATCC No.
Priyanka Rajvanshi, Hemant Kumar Pant, V. Rani   +2 more
doaj   +1 more source

Comparison of the effectiveness of an oral combination of thiamine, pyridoxine, and cyanocobalamin with parenteral cyanocobalamin in adolescents with nutritional vitamin B12 deficiency

Gülhane Tıp Dergisi
Aims: Nutritional vitamin B12 deficiency remains a significant public health issue. This study aimed to compare the efficacy of an oral combination of thiamine, pyridoxine, cyanocobalamin, and parenteral cyanocobalamin treatment among adolescents with ...
Ömer Güneş, Mehmet Ağıllı, Fatih Üçkardeş, Yüksel Hakan Aydoğmuş, Bahar Öztelcan Gündüz, Erman Ataş   +5 more
doaj   +1 more source

Effect of Supplemental Cyanocobalamin on the Growth Performance and Hematological Indicators of the White Pekin Ducks from Hatch to Day 21

Animals, 2019
The experiment was conducted to evaluate the requirement of cyanocobalamin of male Pekin ducks from hatch to 21 days of age. A total of three-hundred-eighty-four, one-day-old meat-type male Pekin ducks were randomly allocated to six treatments, i.e ...
Zaheer Ahmad, Ming Xie, Yongbao Wu, Shuisheng Hou   +3 more
doaj   +1 more source

Cyanocobalamin Ultraflexible Lipid Vesicles: Characterization and In Vitro Evaluation of Drug-Skin Depth Profiles

Pharmaceutics, 2021
Atopic dermatitis (AD) and psoriasis are the most common chronic inflammatory skin disorders, which importantly affect the quality of life of patients who suffer them.
Antonio José Guillot, Enrique Jornet-Mollá, Natalia Landsberg, Carmen Milián-Guimerá, M. Carmen Montesinos, Teresa M. Garrigues, Ana Melero   +6 more
doaj   +1 more source

Neurological complications and pathogenetic therapy for chronic nitrous oxide intoxication (“laughing gas”) in nightclub visitors

Нервно-мышечные болезни, 2020
Background. Nitrous oxide abuse (“laughing gas”, N2O) is common among young people attending nightclubs. Contrary to popular belief about the safety of N2O, in some cases neurological complications develop due to a deficiency of vitamin B12, the activity
N. А. Suponeva, D. А. Grishina, D. А. Grozova, N. V. Belova, М. А. Ginzberg, А. S. Rizvanova, М. А. Piradov   +6 more
doaj   +1 more source

Preparation of yeast Saccharomyces cerevisiae biomass enriched with ergosterol and cyanocobalamin [PDF]

BIO Web of Conferences
Chemical synthesis of vitamins B12 and D2, important nutrients for living organisms, is difficult due to the asymmetric structure of the molecules of these vitamins.
Fatkullin Rinat I., Kalinina Irina V., Goryacheva Sofya A., Stepanova Darya S., Erykalova Vasilina D.   +4 more
doaj   +1 more source

Refining Knowledge of Factors Affecting Vitamin B₁₂ Concentration in Bovine Milk

Animals, 2021
Milk is an excellent source of vitamin B12 (B12) for humans. Therefore, being able to guarantee a high and consistent concentration of this vitamin would enhance consumer perception of milk as a health food.
Mélissa Duplessis, Annie Fréchette, William Poisson, Lya Blais, Jennifer Ronholm   +4 more
doaj   +1 more source