Biosynthesis of the Biphenomycin Family of Potent Antibiotics
The complete biosynthetic pathway of the biphenomycin antibiotics is elucidated, revealing a unique enzymatic machinery featuring a bifunctional MNIO, a regioselective arginase, a B12‐dependent rSAM for C,C coupling, hydroxylation enzymology, and a metalloprotease with dual‐specificity.
Elisabeth Strunk +7 more
wiley +1 more source
Efficacy of methylcobalamin to normalise elevated homocysteine of vitamin B12 deficient vegetarians: a double blind placebo control study [PDF]
Vegetarians are known to be deficient in vitamin B12, due to a lack of dietary animal products, which can elevate plasma total homocysteine (tHcy). Elevated total tHcy can render vegetarians susceptible to cardiovascular disease (CVD).
Chappell, David +3 more
core +1 more source
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem +5 more
wiley +1 more source
Roles of Dietary Cobalt and Administration of Mixed Rumen Bacteria in Regulating Hematological Parameters of Pre-weaning Twin Lambs [PDF]
Cobalt (Co) is required by rumen microorganism for vitamin B12 synthesis. Vitamin B12 is an important cofactor for methionine synthesis and gluconeogenesis.
Adelina, T. (T) +5 more
core
Nanoparticle transport in epithelial cells: pathway switching through bioconjugation [PDF]
The understanding and control of nanoparticle transport into and through cellular compartments is central to biomedical applications of nanotechnology. Here, it is shown that the transport pathway of 50 nm polystyrene nanoparticles decorated with vitamin
Alexander, Cameron +9 more
core +1 more source
Effective pretreatment of wet microalgal biomass to enhance lipid extraction in biodiesel production
Abstract Biodiesel is a viable alternative to fossil fuels. Identifying and evaluating nonedible sources is essential to address ecological concerns and meet energy demands. Microalgae are effective for lipid production but their rigid cell walls hinder bioproduct release making the process energy‐intensive and costly.
Amarnath Krishnamoorthy +2 more
wiley +1 more source
Adaptive Algal Cultivation Enabled by a Monthly Biomass Forecasting System
The developed monthly algal forecasting system used to predict biomass production for two algal strains (A and B) at two pond water depths (low and high). The highest predicted production, achieved with strain A at a low pond water depth, is selected as the cultivation strategy to guide the next month's algal growth.
Hongxiang Yan +5 more
wiley +1 more source
Anemia in Antiretroviral Naïve HIV/AIDS Patients: A Study from Eastern India [PDF]
Background: Hematological manifestations are common throughout the course of HIV infection. Impact of anemia is the most significant among them. The present study was undertaken to evaluate the etiologies underlying anemia in HIV/AIDS. Methods This was a
Banerjee, A +6 more
core +1 more source
Patients with inflammatory bowel disease (IBD) are usually advised to supplement various types of vitamin B12, because vitamin B12 is generally absorbed in the colon. Thus, in the current study, the influence of cyanocobalamin (CNCBL) or methylcobalamin (
Xuan Zhu +12 more
semanticscholar +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source

