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From Polyhalides to Polypseudohalides: Chemistry Based on Cyanogen Bromide.

Angewandte Chemie, 2019
Pseudohalogens are defined as a molecular entity that resemble the halogens in their chemistry. While our understanding of polyhalogen chemistry increased over the last years, the research on polypseudohalogen compounds is lacking. The pseudohalogen BrCN
Benjamin Schmidt   +4 more
semanticscholar   +1 more source

Integration of Bromine and Cyanogen Bromide Generators for the Continuous-Flow Synthesis of Cyclic Guanidines.

Angewandte Chemie, 2017
A continuous-flow process for the in situ on-demand generation of cyanogen bromide (BrCN) from bromine and potassium cyanide that makes use of membrane-separation technology is described.
Gabriel Glotz   +3 more
semanticscholar   +1 more source

Cleavage of transferrin by cyanogen bromide

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1972
Human serum transferrin treated with CNBr and then succinylated was separable into two fractions in ww ratio of 3–4:1 by gel filtration. The larger fraction, Mr 60 000, was homogeneous and contained all the carbohydrate originally present in transferrin. It separated into at least three fragments upon reduction-alkylation and starch gel electrophoresis.
Anatoly Bezkorovainy, Dietmar Grohlich
openaire   +3 more sources

Cleavage of horse immunoglobulin by cyanogen bromide

Immunochemistry, 1968
Abstract Treatment of horst IgG with cyanogen bromide in 0·1 M MCl under specified conditions resulted in the cleavage of about two-thirds of its methionyl peptide bonds. A major fragment of about 5 S was isolated from the reaction mixture by gel filtration.
Michael Sela, Mary Lou Ernst, Ruth Arnon
openaire   +3 more sources

Cleavage of cytochrome c with cyanogen bromide

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1970
Abstract Heme peptides and nonheme peptides suitable for use in binding studies have been prepared by cleavage of horse cytochrome c with cyanogen bromide. These derivatives include a heme peptide of 65 residues and a peptide of 39 residues obtained by division of the protein at the bond following methionine residue 65.
Giampietro Corradin, Henry A. Harbury
openaire   +3 more sources

Structural studies on stem bromelain. Cyanogen bromide cleavage and amino acid sequence of carboxyl-terminal half of the molecule.

International journal of peptide & protein research, 2009
Stem bromelain was cleaved with cyanogen bromide, and the products were fractionated with and without prior maleylation and sulfitolysis. The fragments that corresponded to the carboxyl-terminal half of the molecule were isolated and nearly completely ...
K. Goto, N. Takahashi, T. Murachi
semanticscholar   +1 more source

Coupling of Polysaccharides to Erythrocytes by Cyanogen Bromide

Scandinavian Journal of Immunology, 1974
A simple procedure for covalent coupling of polysaccharides (PS) to erythrocytes for passive hemagglutination is described. The PS is dissolved in saline and activated by adding cyanogen bromide, keeping the pH at 10.7. After adjusting the pH to 7.8, the activated PS solution is admixed to a 2% erythrocyte suspension for coupling, for 2 hr.
L. Kågedal, A. W. Richter
openaire   +3 more sources

Domain characteristics of the cyanogen bromide fragment 121-316 of thermolysin.

International journal of peptide & protein research, 2009
The molecule of thermolysin was shown by X-ray crystallography to be composed of two structural domains of equal size comprising residues 1-157 and 158-316.
C. Vita, D. Dalzoppo, A. Fontana
semanticscholar   +1 more source

The von Braun Cyanogen Bromide Reaction

, 2011
The reaction of a tertiary amine with cyanogen bromide was first described in 1900 by Julius von Braun who elaborated the reaction to such an extent that it bears his name.
H. Hageman
semanticscholar   +1 more source

Isolation and partial sequence of the cyanogen bromide peptides from calf thymus non-histone chromosomal protein HMG 1.

International journal of peptide & protein research, 2009
Peptides produced by cyanogen bromide cleavage of non-histone chromosomal protein HMG 1 have been isolated and characterized, and their partial sequences determined.
J. Walker, B. M. Parker, E. W. Johns
semanticscholar   +1 more source

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