Results 41 to 50 of about 186,970 (263)

Syntheses of Furo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines and Furo[2`,3`: 5,6]-pyrimido[3,4-b][2,3-e]indolo[1,2,4]triazine as a New Ring System

open access: yesMolecules, 2000
2-Amino-4,5-di-(2-furyl)furan-3-carbonitrile (1) reacted with triethyl orthoacetate to afford the corresponding 2-ethoxyimine derivative (2). The latter compound reacted with phenyl hydrazine, p-fluorobenzylamine and sodium hydrogen sulfide, respectively,
Nasser A. Hassan
doaj   +1 more source

Development of a method for measuring mass concentration of cyanides in soil samples using gas chromatography and tandem mass-selective detection

open access: yesВестник войск РХБ защиты, 2020
The Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on Their Destruction places CN-containing toxic chemicals like tabun and its numerous homologues and analogues (around 10.000 organic compounds),
D. O. Korneev   +4 more
doaj   +1 more source

Design, Dimerization, and Recombinant Production of MCh-AMP1–Derived Peptide in Escherichia coli and Evaluation of Its Antifungal Activity and Cytotoxicity

open access: yesFrontiers in Fungal Biology, 2021
Fungal species resistant to current antifungal agents are considered as a serious threat to human health, the dilemma that has dragged attentions toward other sources of antifungals such as antimicrobial peptides (AMPs).
Sima Sadat Seyedjavadi   +9 more
doaj   +1 more source

Fragments of Locusta migratoria apoLp-III provide insight into lipid binding

open access: yesBBA Advances, 2021
Apolipophorin III (apoLp-III) from Locusta migratoria is an exchangeable apolipoprotein with a critical role in lipid transport in insects. The protein is composed of a bundle of five amphipathic α-helices which undergo a large conformational change upon
Blair A. Russell   +2 more
doaj   +1 more source

Chemical Methods for Peptide and Protein Backbone Cleavage

open access: yesChemistryEurope, EarlyView.
Protein cleavage plays essential roles in biology and is powerful for protein manipulation and functionalization as well as in recombinant expression and purification. Here, the historical background and most recent examples of chemical methods for protein and peptide backbone cleavage are discussed (part of the figure was generated in BioRender).
Miguel Angel Alena‐Rodriguez   +1 more
wiley   +1 more source

Synthesis and Characterization of Periodic Polypeptides Containing Repeating —(AlaGly)_xGluGly— Sequences [PDF]

open access: yes, 1992
We have expressed in E. coli a series of periodic polypeptides represented by sequence 1. Our objective has been an understanding of the role of chemical sequence in determining the chain folding behavior of periodic macromolecules.
Borbely, Janos   +5 more
core   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Tri-partite complex for axonal transport drug delivery achieves pharmacological effect. [PDF]

open access: yes, 2010
BACKGROUND: Targeted delivery of pharmaceutical agents into selected populations of CNS (Central Nervous System) neurons is an extremely compelling goal.
Abell, Chris   +12 more
core   +3 more sources

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

open access: yesInsect Molecular Biology, EarlyView.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin   +4 more
wiley   +1 more source

Amino acid sequence of rabbit apolipoprotein E.

open access: yesJournal of Lipid Research, 1991
The complete amino acid sequence of rabbit apolipoprotein E (apoE) was determined by generating three sets of peptides using cyanogen bromide, endoproteinase AspN, and Staphylococcus aureus V8 protease to cleave the protein.
BR Lee   +6 more
doaj   +1 more source

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