Results 71 to 80 of about 186,970 (263)

Cyanogen Bromide Fragments of Human Serum Albumin

open access: yesJournal of Biological Chemistry, 1971
Abstract CNBr cleaves nonreduced human serum albumin into three large fragments, A, B, and C, which account for the total amino acid composition of albumin. Reduction and carboxamidomethylation of the free —SH groups produce four subfragments from A, identified according to their NH2-terminal amino acid residues as A-ProI (32 residues), A-AsxI (38 ...
R H, McMenamy, H M, Dintzis, F, Watson
openaire   +2 more sources

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

open access: yesMass Spectrometry Reviews, Volume 44, Issue 5, Page 715-756, September/October 2025.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen   +9 more
wiley   +1 more source

Amino acid sequences of proteins from Leptospira serovar pomona

open access: yesMemorias do Instituto Oswaldo Cruz, 2000
This report describes a partial amino acid sequences from three putative outer envelope proteins from Leptospira serovar pomona. In order to obtain internal fragments for protein sequencing, enzymatic and chemical digestion was performed.
Alves Selmo F   +2 more
doaj  

Identification of mimotope of Mycoplasma pneumoniae P1 protein and its potential value in serodiagnosis

open access: yesBiotechnology & Biotechnological Equipment, 2019
Traditional diagnostic methods cannot meet the requirements for rapid diagnosis of Mycoplasma pneumoniae. Therefore, developing a serological diagnostic method with high specificity and sensitivity is urgent.
Wenyuan Shi   +4 more
doaj   +1 more source

Non-Cytotoxic Quantum Dot–Chitosan Nanogel Biosensing Probe for Potential Cancer Targeting Agent

open access: yesNanomaterials, 2015
Quantum dot (Qdot) biosensors have consistently provided valuable information to researchers about cellular activity due to their unique fluorescent properties. Many of the most popularly used Qdots contain cadmium, posing the risk of toxicity that could
Tyler Maxwell   +6 more
doaj   +1 more source

Fine Modulation of the Catalytic Properties of Rhizomucor miehei Lipase Driven by Different Immobilization Strategies for the Selective Hydrolysis of Fish Oil

open access: yesMolecules, 2020
Functional properties of each enzyme strictly depend on immobilization protocol used for linking enzyme and carrier. Different strategies were applied to prepare the immobilized derivatives of Rhizomucor miehei lipase (RML) and chemically aminated RML ...
Maryam Yousefi   +5 more
doaj   +1 more source

Structural relationship between link proteins and proteoglycan monomers [PDF]

open access: yes, 1986
Structural homologies between link proteins and proteoglycan monomers are demonstrated. A possible redundancy in the proteoglycan monomers structure is discussed and the link proteins domains homologous to other proteins are ...
J.-P. Périn   +11 more
core   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

open access: yesExploration, Volume 5, Issue 4, August 2025.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang   +6 more
wiley   +1 more source

Effect of apolipoprotein C-I peptides on the apolipoprotein E content and receptor-binding properties of beta-migrating very low density lipoproteins.

open access: yesJournal of Lipid Research, 1994
To evaluate the role of apolipoprotein (apo) C-I in inhibiting lipoprotein binding to the low density lipoprotein receptor-related protein (LRP), a putative lipoprotein remnant receptor, apoC-peptide fragments were prepared by chemical synthesis or by ...
J B Swaney, K H Weisgraber
doaj   +1 more source

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