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Metabolism of cyanogenic glycosides: A review
Food and Chemical Toxicology, 2019Potential toxicity of cyanogenic glycosides arises from enzymatic degradation to produce hydrogen cyanide. Information on the metabolism of cyanogenic glycosides is available from in vitro, animal and human studies. In the absence of β-glucosidase enzymes from the source plant material, two processes appear to contribute to the production of cyanide ...
Peter Cressey, John Reeve
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A cyanogenic glycoside from Canthium schimperianum
Phytochemistry, 1996A new cyanogenic glycoside esterified with an iridoid glycoside, 2R-[(2-methoxybenzoylgenoposidyl)-5-O-beta-D-apiofuranosyl-( 1-->6)-beta-glucopyranosyloxy]-2-phenyl acetonitrile, was isolated from the seeds of Canthium schimperianum and identified from its spectroscopic data.
B, Schwarz, V, Wray, P, Proksch
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Biosynthesis of cyanogenic glycosides
Naturwissenschaften, 1979Cyanogenic glycosides are secondary plant compounds that occur widely in the plant kingdom. They are the source of HCN which can render the plant toxic if it is taken as food. The enzymes responsible for production of the HCN have long been known.
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Cyanogenic glycosides of the Turneraceae
Biochemical Systematics and Ecology, 1985Eighty species of Turneraceae were tested and found to be cyanogenic. Analysis by HPLC and NMR and comparisons of Rt values from paper chromatograms showed all to possess tetraphyllin A and B and epitetraphyllin B and deidaclin as their cyanogens. These data confirm the close relationship of this family with other families which produce structurally ...
K.C. Spencer, D.S. Seigler, S.W. Fraley
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Toxicity of cyanogenic glycosides
Food Chemistry, 1980Abstract The toxicity of cyanogenic glycosides is reviewed in the context of their metabolic involvement with goitre and tropical ataxis neuropathy (TAN). The significance of toxicity data is logically related to the nutritional adequacy of diet.
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Field desorption mass spectrometry of cyanogenic glycosides
Biological Mass Spectrometry, 1980The field desorption mass spectra of several underivatized cyanogenic glycosides exhibit molecular ions or ions derived from the parent compound by protonation and alkali metal cationization. Abundant fragment ions are present and can be readily related to structure. Significant deviations from established fragmentation pathways are observed due to the
P A, Dreifuss +5 more
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Cyanogenic Glycosides: Synthesis, Physiology, and Phenotypic Plasticity
Annual Review of Plant Biology, 2014Cyanogenic glycosides (CNglcs) are bioactive plant products derived from amino acids. Structurally, these specialized plant compounds are characterized as α-hydroxynitriles (cyanohydrins) that are stabilized by glucosylation. In recent years, improved tools within analytical chemistry have greatly increased the number of known CNglcs by enabling the ...
Gleadow, Roslyn M. +1 more
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Synthesis of Degraded Cyanogenic Glycosides From Sambucus Nigra
Natural Product Research, 2003Two natural cyanohydrins, isolated from Sambucus nigra, have been synthesised from mandelonitrile and penta-O-acetyl-beta-galactopyranose. The synthesis confirmed the stereochemistry of the compounds, which had been assigned on biogenetic grounds.
DELLA GRECA M +5 more
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Note: A novel cyanogenic glycoside from Semiaquilegia adoxoides
Journal of Asian Natural Products Research, 2005Phytochemical investigation of Semiaquilegia adoxoides was initiated in view of its common usage in traditional Chinese medicine and the scarcity of previous phytochemical studies. Fractionation of an ethanol extract from the roots of this plant led to the isolation and identification of a novel cyanogenic glycoside, 2-(beta-D-glucopyranosyloxy)-4 ...
Yan-Fang, Su +3 more
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Analysis of cyanogenic glycosides by micellar capillary electrophoresis
Journal of Chromatography B: Biomedical Sciences and Applications, 2000The separation of amygdalin, prunasin and their isomers neoamygdalin and sambunigrin could be achieved with micellar capillary electrophoresis (MEKC). The two isomers were obtained in alkaline conditions and were produced in less than 15 min at pH 11.0.
CAMPA C. +5 more
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