Results 141 to 150 of about 444 (255)

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown   +2 more
wiley   +1 more source

Peer effects at work on parental leave: Why is Papa not more involved?

open access: yesCanadian Journal of Economics/Revue canadienne d'économique, EarlyView.
Abstract We estimate the peer effects of paternity leave‐taking among male co‐workers using the 2006 Quebec paternity leave reform. Using high‐quality administrative data, we closely follow the birth date regression discontinuity research design of Dahl et al.
Yaya Diallo, Fabian Lange
wiley   +1 more source

Adolescents' self‐diagnosis of mental disorders: a qualitative study of mental health clinicians' perspectives

open access: yesChild and Adolescent Mental Health, EarlyView.
Background Concerns over self‐diagnosis of mental disorders among adolescents have been increasing, but very little empirical research exists to understand what clinicians think about this phenomenon or how it might impact psychological therapy. Methods Semi‐structured one‐to‐one interviews were conducted with 16 mental health professionals, exploring ...
Katie Cunningham‐Rowe, Lucy Foulkes
wiley   +1 more source

IMAGINE Personalities: Augmenting Digital Character Workflows Using Motion Capture, Wearable Sensors, and Live Coding. [PDF]

open access: yesSensors (Basel)
Baltas D   +14 more
europepmc   +1 more source

Oral Health and Well‐Being: Insights From Personal Narratives of Losing Teeth and Living With Dentures

open access: yesCommunity Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To explore how individuals who have lost or have missing teeth and subsequently received dentures make sense of the factors influencing their oral health and well‐being. Methods Thematic and structural narrative analysis was used to evaluate 19 semi‐structured interview transcripts from a secondary dataset of United Kingdom adults ...
Heba Ramadan Salama   +3 more
wiley   +1 more source

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