Results 151 to 160 of about 8,652,661 (302)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Nitrogen Cycling and Community Structure of Proteobacterial β-Subgroup Ammonia-Oxidizing Bacteria within Polluted Marine Fish Farm Sediments [PDF]

, 1999
Allison E. McCaig, Carol J. Phillips, J. Stephen, George A. Kowalchuk, S. M. Harvey, R. A. Herbert, T. Martin Embley, James I. Prosser   +7 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Forecasting the number of sunspots for solar cycle 25 utilizing the facebook prophet model. [PDF]

Sci Rep
Rahman HIA, Badawy WA.
europepmc   +1 more source

The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

, 2018
Audra N. Iness, Jessica Felthousen, Varsha Ananthapadmanabhan, Fatmata Sesay, Siddharth Saini, Keelan Z. Guiley, Seth M. Rubin, Mikhail G. Dozmorov, Larisa Litovchick   +8 more
openalex   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The diverse roles of Hox proteins in the regulation of the cell cycle and their therapeutic value in cancer treatment. [PDF]

Cancer Metastasis Rev
Vakafua L, Clifton-Bligh L, Seyedasli N.
europepmc   +1 more source

Exergy and economic analyses of replacing feedwater heaters in a Rankine cycle with parabolic trough collectors

, 2018
Amin Mohammadi, Mohammad Hossein Ahmadi, Mokhtar Bidi, Mahyar Ghazvini, Tingzhen Ming   +4 more
openalex   +1 more source

Cycling and sports, but not walking, are associated with 10-year cardiovascular disease incidence: the MORGEN Study [PDF]

, 2010
Marieke P. Hoevenaar‐Blom, Wanda Wendel‐Vos, Annemieke M. W. Spijkerman, Daan Kromhout, WMM Verschuren   +4 more
openalex   +1 more source