Results 171 to 180 of about 8,652,661 (302)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Ultrafast Synthesis of Large‐Sized and Conductive Na₃V₂(PO₄)₂F₃ Simultaneously Approaches High Tap Density, Rate and Cycling Capability [PDF]

Zijing Song, Yuhang Liu, Zhaoxin Guo, Zhedong Liu, Zekun Li, Jieshu Zhou, Wei‐Di Liu, Rui Liu, Jingchao Zhang, Jiawei Luo, Haoran Jiang, Jia Ding, Wenbin Hu, Yanan Chen   +13 more
openalex   +1 more source

The ubiquitin ligase HACE1 regulates Golgi membrane dynamics during the cell cycle [PDF]

, 2011
Danming Tang, Yi Xiang, Stefano De Renzis, Jochen C. Rink, Gen Zheng, Marino Zerial, Yanzhuang Wang   +6 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Comprehensive profiling of chromatin occupancy dynamics through the cell cycle. [PDF]

Nucleic Acids Res
Li Y, MacAlpine DM, Hartemink AJ.
europepmc   +1 more source

Organic rankine cycle versus steam cycle : a thermodynamic comparison [PDF]

, 2012
De Paepe, Michel, van den Broek, Martijn, Vanslambrouck, Bruno   +2 more
core   +1 more source

Techno-economic assessment of green hydrogen production integrated with hybrid and organic Rankine cycle (ORC) systems [PDF]

Suresh Baral, Juraj Šebo
openalex   +1 more source

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells [PDF]

, 2012
Norman Sachs, Pablo Secades, Laura van Hulst, Maaike Kreft, Ji‐Ying Song, Arnoud Sonnenberg   +5 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Balance and imbalance in dark and bright (OFF and ON) visual channels. [PDF]

Sci Rep
Greene E, Morrison J.
europepmc   +1 more source