Results 191 to 200 of about 9,877,914 (299)

Cyclic-di-GMP controls Type III effector export and symptom development in Pseudomonas syringae infections via the export ATPase HrcN. [PDF]

PLoS Pathog
Ward D, Little RH, Thompson CMA, Malone JG.   +3 more
europepmc   +1 more source

A Second Role for the Second Messenger Cyclic-di-GMP in E. coli: Arresting Cell Growth by Altering Metabolic Flow. [PDF]

mBio, 2023
Hwang Y, Harshey RM.
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Cyclic-di-GMP interferes with DNA-MucR-DNA bridging to derepress genes targeted by the xenogeneic silencer MucR. [PDF]

Nucleic Acids Res
Liu NN, Li ML, Shi WT, Jiao J, Xu YH, Tian Y, Guo JN, Chen YQ, Tong H, Tian CF.   +9 more
europepmc   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

The <i>Pseudomonas aeruginosa</i> Cpx system provides a cyclic-di-GMP independent link between cell envelope stress and surface sensing. [PDF]

mBio
O'Malley MR, Dearing HN, Zheng X, Kretschmer AN, Cho TH-S, Raivio TL, Parsek MR.   +6 more
europepmc   +1 more source

A Library of Promoter-gfp Fusion Reporters for Studying Systematic Expression Pattern of Cyclic-di-GMP Metabolism-Related Genes in Pseudomonas aeruginosa. [PDF]

Appl Environ Microbiol, 2023
Liu D, Wang D, Wei Q, Zhang Y, Yu H, Ma LZ.   +5 more
europepmc   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

A cyclic di-GMP phosphodiesterase in the VSP-2 island of <i>Vibrio cholerae</i> is regulated by zinc and quorum sensing. [PDF]

mBio
Rangarajan AA, Ok K, Malleck MK, Ferrell MJ, O'Halloran TV, Waters CM.   +5 more
europepmc   +1 more source

Cyclic di-GMP Regulates the Type III Secretion System and Virulence in Bordetella bronchiseptica. [PDF]

Infect Immun, 2022
Gutierrez MP, Wong TY, Damron FH, Fernández J, Sisti F.   +4 more
europepmc   +1 more source