Results 211 to 220 of about 9,877,914 (299)

Genome characterization of a uropathogenic <i>Pseudomonas aeruginosa</i> isolate PA_HN002 with cyclic di-GMP-dependent hyper-biofilm production. [PDF]

Front Cell Infect Microbiol, 2022
Lin S, Chen S, Li L, Cao H, Li T, Hu M, Liao L, Zhang LH, Xu Z.   +8 more
europepmc   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

Responsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun, Meiqi Li, Di Nan, Jiaqi Zhao, Yu Chen, Yao Gao, Shichen Zhang, Kirsten L. Van Landuyt, Manlin Qi   +8 more
wiley   +1 more source

Crucial roles of intracellular cyclic di-GMP in impacting the genes important for extracellular electron transfer by <i>Geobacter metallireducens</i>. [PDF]

Appl Environ Microbiol
Jiang Y, Sun L, Hou L, Hu Y, Jiang Z, Dong Y, Song H, Shi L.   +7 more
europepmc   +1 more source

Double take: A dual-functional Hypr GGDEF synthesizes both cyclic di-GMP and cyclic GMP-AMP to control predation in Bdellovibrio bacteriovorus. [PDF]

PLoS Genet, 2022
Rangarajan AA, Waters CM.
europepmc   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

Molecular characterization and inhibition of cyclic-di-GMP receptor proteins in <i>Pseudomonas aeruginosa</i>: INSIGHTS from docking and dynamics studies. [PDF]

Biochem Biophys Rep
Yakobi SH, Ramaloko W, Maningi NE.
europepmc   +1 more source

Cyclic di-GMP modulates sessile-motile phenotypes and virulence in Dickeya oryzae via two PilZ domain receptors. [PDF]

Mol Plant Pathol, 2022
Chen Y, Lv M, Liang Z, Liu Z, Zhou J, Zhang LH.   +5 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

The cyclic di-GMP receptor YcgR links the second messenger with the putrescine quorum sensing system in modulation of <i>Dickeya oryzae</i> motility. [PDF]

mBio
Gu W, Chen Y, Xie C, Chen Z, Gao H, Zhu Y, Zhang L-h, Liao L.   +7 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source