“Cyclic nucleotides in plants: from obscure messengers to central regulators“
Frontiers in Plant ScienceThis review examines the historical trajectory of cyclic nucleotides (cNMPs) research in plants, a field that has encountered prolonged challenges and skepticism, contrasting sharply with its rapid validation in animal systems.
Brygida Świeżawska-Boniecka +1 more
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Molecules, 2015 Chinese jujube (Ziziphus jujuba), a medicinal and edible plant, is widely consumed in Asian countries owing to the remarkable health activities of its fruits.
Sheng Guo +6 more
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Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors. [PDF]
, 1996 Ariane Mallat +12 more
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Dynamical strategies for obstacle avoidance during Dictyostelium discoideum aggregation: a Multi-agent system model [PDF]
, 2019 Chemotaxis, the movement of an organism in response to chemical stimuli, is a typical feature of many microbiological systems. In particular, the social amoeba \textit{Disctyostelium discoideum} is widely used as a model organism, but it is not still ...
Maggiora, Marco, Proverbio, Daniele
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Platelet-derived adenosine 5′-triphosphate suppresses activation of human hepatic stellate cell: In vitro study [PDF]
, 2011 Keywords: adenosine; adenosine 5′-triphosphate; cyclic adenosine 5′-monophosphate; hepatic stellate cell; liver fibrosisAim: Activated hepatic stellate cells (HSC) play a critical role in liver fibrosis.
Fukunaga Kiyoshi +16 more
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Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy
Carbon Energy, EarlyView.Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian +3 more
wiley +1 more source
Acyclic Nucleoside Phosphonates As Potential Inhibitors Of Plasmodium Falciparum Egress
Chemistry – A European Journal, EarlyView.Exploration of the chemistry of acyclic nucleoside phosphonates allowed us to study structural diversity from the hit compound; biological evaluation and molecular docking were performed to decipher key interactions with the putative target. Abstract The emergence of drug‐resistant Plasmodium strains requires the development of novel antimalarial ...
Thomas Cheviet +6 more
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Cyclic Nucleotide Monophosphates and Their Cyclases in Plant Signaling
Frontiers in Plant Science, 2017 The cyclic nucleotide monophosphates (cNMPs), and notably 3′,5′-cyclic guanosine monophosphate (cGMP) and 3′,5′-cyclic adenosine monophosphate (cAMP) are now accepted as key signaling molecules in many processes in plants including growth and ...
Chris Gehring +3 more
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ChemMedChem, EarlyView.The design, synthesis, and initial biological evaluation of noncovalent stimulator of interferon genes degraders are presented. The lead from this series, BH690L, exhibits an effective concentration for half‐maximal degradation (DC50) of 11.3 nM and a maximum level of degradation (Dmax) of 0.67.
Bo Hu, Adam S. Duerfeldt
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cAMP Accumulation Assays Using the AlphaScreen® Kit (PerkinElmer)
Bio-Protocol, 2013 Cyclic adenosine monophosphate (cAMP) is an intracellular signaling messenger derived from the catalytic conversion of ATP, and is a major product of activated Gs protein-coupled receptors. Conversely, formation of cAMP is inhibited by Gi protein-coupled
Cassandra Koole +2 more
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