British Journal of Pharmacology, EarlyView.Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source
Soy isoflavone yeast fermented extract inhibits contraction of rat ileal smooth muscle via opening of K<sup>+</sup> channels and activation of intracellular cyclic adenosine monophosphate- and cyclic guanosine monophosphate-related pathways. [PDF]
J Vet Med SciYamazaki S +4 more
europepmc +1 more source
Adenosine 3′:5′-cyclic monophosphate-binding protein from the cellular slime mould Dictyostelium discoideum (Short Communication) [PDF]
, 1973 A M Malkinson +2 more
openalex +1 more source
Compartmentalisation in cAMP signalling: A phase separation perspective
British Journal of Pharmacology, EarlyView.Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source
Differences in the Effectiveness of Uridine and <i>Liriope platyphylla</i> L. Between Complement Component 3 Deficiency- and Loperamide-Induced Constipation May Be Associated with the Alternative Regulation of the Cyclic Adenosine Monophosphate Downstream Signaling Pathway. [PDF]
Pharmaceuticals (Basel)Song HJ +11 more
europepmc +1 more source
Cyclic Adenosine Monophosphate-Enhanced Calvarial Regeneration by Bone Marrow-Derived Mesenchymal Stem Cells on a Hydroxyapatite/Gelatin Scaffold. [PDF]
ACS Omega, 2021 Ju T, Zhao Z, Ma L, Li W, Li S, Zhang J.
europepmc +1 more source