Results 231 to 240 of about 233,579 (364)

HIV-1 gp120 Impairs Spatial Memory Through Cyclic AMP Response Element-Binding Protein. [PDF]

Front Aging Neurosci, 2022
Shrestha J, Santerre M, Allen CNS, Arjona SP, Merali C, Mukerjee R, Chitrala KN, Park J, Bagashev A, Bui V, Eugenin EA, Merali S, Kaul M, Chin J, Sawaya BE.   +14 more
europepmc   +1 more source

Intracellular cyclic AMP production enhanced by a hormone receptor transferred from a different cell. beta-adrenergic responses in cultured cells conferred by fusion with turkey erythrocytes

, 1978
Dennis Schulster, Joseph Orly, G. Seidel, M. Schramm   +3 more
openalex   +1 more source

Affinity labeling of the catalytic subunit of cyclic AMP-dependent protein kinase by N alpha-tosyl-L-lysine chloromethyl ketone. [PDF]

, 1979
Abraham Kupfer, Viviane Gani, Juan S. Jiménez, Shmuel Shaltiel   +3 more
openalex   +1 more source

Enhanced Media Optimize Bovine Myogenesis in 2D and 3D Models for Cultivated Meat Applications

Advanced Science, EarlyView.
This study uses multiomics approaches to characterize bovine myogenesis in vitro, identifying media components that enhance myogenic progenitor cell differentiation in 2D and 3D models. Notably, the enhanced conditions promoted formation of unique cell populations and contractile muscle cells expressing mature myogenic markers.
Christine L. Trautmann, Adhideb Ghosh, Ali Kerem Kalkan, Falko Noé, Ori Bar‐Nur   +4 more
wiley   +1 more source

Comparative studies on cyclic AMP binding and protein kinase in cyclic AMP-responsive and -unresponsive Walker 256 mammary carcinomas.

, 1977
Yoon S. Cho‐Chung, Timothy Clair, Ping Yi, Clifford Parkison   +3 more
openalex   +1 more source

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng   +11 more
wiley   +1 more source

NFκB and Cyclic AMP Response Element Sites Mediate the Valproic Acid and UL138 Responsiveness of the Human Cytomegalovirus Major Immediate Early Enhancer and Promoter. [PDF]

J Virol, 2023
Albright ER, Walter RM, Saffert RT, Kalejta RF.   +3 more
europepmc   +1 more source

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Advanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou   +14 more
wiley   +1 more source

On Semmler-Wolff Reaction of Oximes of Some α, β-Unsaturated Six-Membered Cyclic Ketones

, 1975
EISAKU HAYASHI, SENJI SUZUKI
openalex   +2 more sources

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source