Results 241 to 250 of about 972,099 (307)
Some of the next articles are maybe not open access.
The measurement of cyclic GMP and cyclic AMP phosphodiesterases
Analytical Biochemistry, 1979Abstract Methods are described for measuring phosphodiesterases for cGMP and cAMP in the range of activity yielding 10 −12 to 10 −8 mol of product. The 5′-GMP formed is measured by conversion to GDP with guanylate kinase. Amounts of GDP greater than 10 −10 mol are measured directly with an enzyme system which results in stoichiometric oxidation of
Joyce G. Carter +2 more
openaire +3 more sources
The role of cyclic AMP and cyclic GMP in byssinosis
American Industrial Hygiene Association Journal, 1979The lungs of female guinea pigs, either untreated or previously sensitized with aqueous extracts of cotton dust (AECD) were perfused via the pulmonary artery with 0, 10-6, 10-5 or 10-4 g/mL of lyophilized AECD in Tyrodes solution. Pressure changes in the pulmonary artery were monitored during this period.
Gerald A. Greenblatt, M H Elissalde
openaire +3 more sources
Annual Review of Pharmacology, 1974
A chapter on "Cyclic AMP and Drug Action" has already been published in Annual Review of Pharmacology (1). In spite of its restrictive title, this paper covered most of the knowledge about the biochemical and biological effects of cAMP that was available in 1969.
openaire +2 more sources
A chapter on "Cyclic AMP and Drug Action" has already been published in Annual Review of Pharmacology (1). In spite of its restrictive title, this paper covered most of the knowledge about the biochemical and biological effects of cAMP that was available in 1969.
openaire +2 more sources
Cyclic AMP in Hypersensitivity Reactions
Allergy, 1979Phytohemagglutinin (PHA) was capable of inducing non‐cytotoxic histamine release from human leucocytes. In the presence of deuterium oxide (D2O), PHA caused significantly greater histamine release. Dibutyryl cyclic AMP id‐cAMP) could enhance the histamine release in the presence of D2O although it was an inhibitor of the release if used alone. However,
F. Anfosso +3 more
openaire +3 more sources
The occurrence of cyclic AMP in archaebacteria
Biochemical and Biophysical Research Communications, 1986Cyclic AMP was found in species representative of the three major groups of the archaebacteria. In Methanobacterium thermoautotrophicum starvation for H2 led to a significant increase in cellular cAMP. The findings suggest that the occurrence of cAMP antedates the divergence of the major kingdoms of biology; the observations also imply that cAMP ...
Howard V. Rickenberg +4 more
openaire +3 more sources
JAMA: The Journal of the American Medical Association, 1974
To the Editor.— Dr. Auerbach reports (227:326, 1974) on the topical use of dibutylated cyclic adenosine monophosphate (cyclic AMP) in patients with psoriasis, the rationale being to elevate the reduced levels of skin cyclic AMP in these people. He observed either no improvement or worsening of lesions and suggests several possible reasons for lack of ...
openaire +3 more sources
To the Editor.— Dr. Auerbach reports (227:326, 1974) on the topical use of dibutylated cyclic adenosine monophosphate (cyclic AMP) in patients with psoriasis, the rationale being to elevate the reduced levels of skin cyclic AMP in these people. He observed either no improvement or worsening of lesions and suggests several possible reasons for lack of ...
openaire +3 more sources
1981
Publisher Summary This chapter discusses the nephrogenous cyclic AMP. The total amount of cyclic AMP (cAMP) excreted is the sum of that derived from two sources, that is, the filtered load of the nucleotide and nephrogenous cAMP. On an average, each component accounts for approximately 50% of the total quantity of cAMP excreted by normal individuals.
openaire +3 more sources
Publisher Summary This chapter discusses the nephrogenous cyclic AMP. The total amount of cyclic AMP (cAMP) excreted is the sum of that derived from two sources, that is, the filtered load of the nucleotide and nephrogenous cAMP. On an average, each component accounts for approximately 50% of the total quantity of cAMP excreted by normal individuals.
openaire +3 more sources
Cyclic AMP Signaling in Trypanosomatids
Parasitology Today, 2000Curative interference with signal transduction pathways is a spectacularly successful concept in many domains of modern pharmacology; indeed, the 'wonder drug' Viagra is but a humble inhibitor of a cyclic GMP (cGMP)-specific phosphodiesterase and, thus, interferes with cGMP-signaling in a strategic organ.
T Seebeck, C Naula
openaire +3 more sources
1976
Microtubules, tubular structures of 240 A diameter, are widely distributed in plant and animal cells (for a review see (1)). These organelles are present in different sites of the cell; they make up the spindle fibres of the mitotic cells and they are prominent in the axons and dendrites of neurons.
Lydie Rappaport +2 more
openaire +2 more sources
Microtubules, tubular structures of 240 A diameter, are widely distributed in plant and animal cells (for a review see (1)). These organelles are present in different sites of the cell; they make up the spindle fibres of the mitotic cells and they are prominent in the axons and dendrites of neurons.
Lydie Rappaport +2 more
openaire +2 more sources
On the Biological Role of Cyclic AMP
JAMA: The Journal of the American Medical Association, 1970Before discussing the role of cyclicadenylate, or adenosine 3′,5′-monophosphate (cyclic AMP) in biology, I would like to make a few brief remarks about another subject, the role of the basic scientist in medicine. I would like to hope that this and the subject that I have been asked to write about are not completely unrelated.
openaire +3 more sources