Results 241 to 250 of about 233,579 (364)

A Mass Spectrometry Approach Reveals Fatty Acid Isomerism in Tomato Cold Tolerance

Advanced Science, EarlyView.
An enhanced mass spectrometry approach reveals fatty acids (FAs) and FA isomers that are critical for tomato cold tolerance. Applying specific FA isomers can partially rescue cold sensitivity in tomato mutant plants, highlighting the importance of FA isomers in plant cold stress adaptation.
Leelyn Chong, Hengxue Shi, Qirui Yu, Xiaoning Shi, Zhaoxing Jia, Ziyun Dong, Yu Xia, Yingfang Zhu   +7 more
wiley   +1 more source

Cholesterol Activates Cyclic AMP Signaling in Metaplastic Acinar Cells. [PDF]

Metabolites, 2021
Grisan F, Spacci M, Paoli C, Costamagna A, Fantuz M, Martini M, Lefkimmiatis K, Carrer A.   +7 more
europepmc   +1 more source

Binding of inhibitor alters kinetic and physical properties of extracellular cyclic AMP phosphodiesterase from Dictyostelium discoideum. [PDF]

, 1979
Richard H. Kessin, Seth J. Orlow, Reneé Shapiro, Jakob Franke   +3 more
openalex   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Abnormal Calcium Handling in Atrial Fibrillation Is Linked to Changes in Cyclic AMP Dependent Signaling. [PDF]

Cells, 2021
Reinhardt F, Beneke K, Pavlidou NG, Conradi L, Reichenspurner H, Hove-Madsen L, Molina CE.   +6 more
europepmc   +1 more source

Discussion of hepatotrophic factors and regeneration [PDF]

, 1975
Putnam, CW, Starzl, TE
core  

Cyclic AMP-Dependent Protein Kinase Activation and the Induction of Ornithine Decarboxylase during Lymphocyte Mitogenesis [PDF]

, 1979
Gary R. Klimpel, Craig V. Byus, Diane Haddock Russell, David O. Lucas   +3 more
openalex   +1 more source

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang, Xiaoxiao Yang, Xue Gao, Xiaoshan Du, Xuegan Lian, Naiyuan Shao, Ye Liu, Zhenning Huang, Dongmei Jia, Alexander Y. L. Lau, Zhiguo Li, Zaal Kokaia, Fu‐Dong Shi, Chao Zhang   +13 more
wiley   +1 more source

Melatonin Modulates Glucose Metabolism Reprogramming via Targeting G6PD to Alleviate Lead‐Induced Hepatocytes Pyroptosis in Common Carp (Cyprinus carpio L.)

Advanced Science, EarlyView.
This study reveals that Lead reprograms glucose metabolism to enhance H3K18la, driving DRP1‐dependent mitochondrial DNA leakage and cGAS‐STING‐mediated pyroptosis. Melatonin targets G6PD to suppress glycolysis‐driven H3K18la and restore mitochondrial homeostasis, thereby alleviating Lead‐induced liver injury in common carp through disruption of the ...
Zhiying Miao, Xiaofeng Ji, Lai Wei, Zhiruo Miao, Shiwen Xu   +4 more
wiley   +1 more source

Activation of cyclic AMP signaling pathway in dopaminergic neurons rescues locomotion defects in a Drosophila larval model of Parkinson's disease. [PDF]

Brain Res
Ismael S, Colvin RA, Lee D.
europepmc   +1 more source