Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity
Advanced Science, EarlyView.This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang +13 more
wiley +1 more source
Participation of cAMP in tacrine-induced gastric smooth muscle relaxation
Open Life Sciences, 2011 Prissadova Natalia +4 more
doaj +1 more source
Cholesterol Activates Cyclic AMP Signaling in Metaplastic Acinar Cells. [PDF]
Metabolites, 2021 Grisan F +7 more
europepmc +1 more source
Cyclic AMP-Mediated Induction of the Cyclic AMP Phosphodiesterase of C-6 Glioma Cells
, 1974 Joan P. Schwartz, Janet V. Passonneau
openalex +1 more source
Cyclic AMP-dependent protein kinase mediates a cyclic AMP-stimulated decrease in ornithine and S-adenosylmethionine decarboxylase activities. [PDF]
, 1978 Paul A. Insel, J. Christopher Fenno
openalex +1 more source
Advanced Science, EarlyView.The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang +9 more
wiley +1 more source
Modulation of Cyclic AMP Levels in Fallopian Tube Cells by Natural and Environmental Estrogens. [PDF]
Cells, 2021 Rosselli M +5 more
europepmc +1 more source
Modulation of Adenylate Cyclase/Cyclic AMP Response by Thyrotropin and Prostaglandin E2 in Cultured Thyroid Cells. 2. Positive Regulation [PDF]
, 1978 Nobuyuki Takasu +3 more
openalex +1 more source
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
Science, 2013 Jiaxi Wu +6 more
semanticscholar +1 more source