Results 271 to 280 of about 233,579 (364)

Glycogen synthase kinases. Distribution in mammalian tissues of forms that are independent of cyclic AMP.

, 1977
Keith K. Schlender, Erwin M. Reimann
openalex   +1 more source

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

Advanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan, Dongxiao Cui, Jiajian Guo, Xiaojing Ma, Jiaming Wang, Linyue Guo, Tianyu Li, Mingrui Yang, Guangrui Huang, Anlong Xu, Wenfu Ma   +10 more
wiley   +1 more source

Cyclic AMP-stimulated protein kinases at brain synaptic junctions.

, 1979
PT Kelly, CW Cotman, Michael Largen
openalex   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science, EarlyView.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source

The hepatic glucose-mobilizing effect of glucagon is not mediated by cyclic AMP most of the time.

Am J Physiol Endocrinol Metab, 2021
Rodgers RL.
europepmc   +1 more source

Correlation of cyclic AMP and cyclic GMP levels with changes in contractile force of dog ventricular myocardium during cholinergic antagonism of positive inotropic actions of histamine, glucagon, theophylline and papaverine.

, 1979
Masao Endoh
openalex   +1 more source

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Cellular metabolism of substance P produces neurokinin-1 receptor peptide agonists with diminished cyclic AMP signaling.

Am J Physiol Cell Physiol
Kriska T, Natarajan J, Herrnreiter A, Park SK, Pfister SL, Thomas MJ, Widiapradja A, Levick SP, Campbell WB.   +8 more
europepmc   +1 more source

Studies on the cyclic 3':5'-AMP-stimulated pig liver protein kinase reaction with pyruvate kinase as substrate.

, 1977
Lars Berglund, Olle Ljungström, Lorentz Engström   +2 more
openalex   +1 more source

The Interplay between the Gut and Ketogenic Diets in Health and Disease

Advanced Science, EarlyView.
This review synthesizes current knowledge on the interaction between ketogenic diets and the gut, covering gut physiology, intestinal immunity, and the gut microbiome. It explores innovative methods for tailoring the diet to maximize benefits while reducing side effects. Emphasis is placed on gut‐mediated mechanisms as a critical interface between diet
Chunlong Mu, Jong M. Rho, Jane Shearer
wiley   +1 more source