Results 271 to 280 of about 1,140,604 (331)
Advanced Science, EarlyView.Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He +10 more
wiley +1 more source
Advanced Science, EarlyView.This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang +10 more
wiley +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Advanced Science, EarlyView.Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
AMMONIA PLUS ANOTHER FACTOR ARE NECESSARY FOR DIFFERENTIATION IN SUBMERGED CLUMPS OF DICTYOSTELIUM [PDF]
, 1979 David, Charles N., Sternfeld, John
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International Journal of Oral Surgery, 1978
Cyclic AMP mediates the effects of many hormones on their target cells. Some of the mechanisms by which this occurs are discussed in this review. The role of cyclic AMP in regulating glycogen metabolism in liver and skeletal muscle is firmly established.
D, Coppe, M L, Steer
openaire +2 more sources
Cyclic AMP mediates the effects of many hormones on their target cells. Some of the mechanisms by which this occurs are discussed in this review. The role of cyclic AMP in regulating glycogen metabolism in liver and skeletal muscle is firmly established.
D, Coppe, M L, Steer
openaire +2 more sources
Journal of Cell Science, 2001
![Figure][1] Cyclic adenosine 3′,5′-monophosphate (cAMP) was the first identified second messenger. A large number of studies during the past 30 years have elucidated the fundamental role of cAMP in the cellular response to many hormones and neurotransmitters.
FIMIA GM, SASSONE-CORSI P
openaire +4 more sources
![Figure][1] Cyclic adenosine 3′,5′-monophosphate (cAMP) was the first identified second messenger. A large number of studies during the past 30 years have elucidated the fundamental role of cAMP in the cellular response to many hormones and neurotransmitters.
FIMIA GM, SASSONE-CORSI P
openaire +4 more sources
Cyclic di-AMP Signaling in Bacteria.
Annual Review of Microbiology, 2020The second messenger molecule cyclic di-AMP (c-di-AMP) is formed by many bacteria and archaea. In many species that produce c-di-AMP, this second messenger is essential for viability on rich medium. Recent research has demonstrated that c-di-AMP binds to
J. Stülke, Larissa Krüger
semanticscholar +1 more source