Results 281 to 290 of about 1,017,209 (339)

Spinal Axon Regeneration Induced by Elevation of Cyclic AMP

open access: yesNeuron, 2002
Jin Qiu   +6 more
semanticscholar   +1 more source

Mechanical Cues Regulate Cargo Sorting and Export at the Golgi

open access: yesAdvanced Science, EarlyView.
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino   +21 more
wiley   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

open access: yesAdvanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun   +16 more
wiley   +1 more source

Effects of Cyclic AMP and Dibutyryl Cyclic AMP on Renin Release in Vivo and in Vitro

open access: bronze, 1973
Kenjiro Yamamoto   +5 more
openalex   +2 more sources

Cyclic di‐AMP mediates biofilm formation

open access: yesMolecular Microbiology, 2016
Xian Peng   +4 more
semanticscholar   +1 more source

Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism

open access: yesAdvanced Science, EarlyView.
Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce   +8 more
wiley   +1 more source

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