Results 291 to 300 of about 233,579 (364)

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

Advanced Science, EarlyView.
This review explores the complex and self‐reinforcing cycle of mechanical stress, inflammation, and altered vascularity in tendinopathy—a common, painful tendon disorder. It integrates current findings on cellular, molecular, and biomechanical mechanisms, highlighting how mechanical overload, inflammatory signals, and abnormal blood vessel behavior ...
Renate Gehwolf, Herbert Tempfer, Nevra Pelin Cesur, Andrea Wagner, Andreas Traweger, Christine Lehner   +5 more
wiley   +1 more source

AMMONIA PLUS ANOTHER FACTOR ARE NECESSARY FOR DIFFERENTIATION IN SUBMERGED CLUMPS OF DICTYOSTELIUM [PDF]

, 1979
David, Charles N., Sternfeld, John
core  

Stirring Without Stirrers: Polymer Fouling‐Driven Mass Transport Unlocks Order‐of‐Magnitude Gain in Electrochemiluminescence

Advanced Science, EarlyView.
Strategic electrode fouling enhances mass transport, primarily through electrochemically actuated lateral density gradients. Engineered fouling induces flow velocities up to 0.4 cm s⁻¹ in otherwise quiescent systems. Sub‐millimeter plastic features boost local rates by up to 290%, while micrometer‐scale arrays yield a 30% net electrolysis gain ...
Wathsala Prasadini Kapuralage, Hemendra Kala, Mariusz Martyniuk, Nadim Darwish, Melanie MacGregor, K. Swaminathan Iyer, Simone Ciampi   +6 more
wiley   +1 more source

Magnetic‐Driven Viscous Mechanisms in Ultra‐Soft Magnetorheological Elastomers Offer History‐Dependent Actuation with Reprogrammability Options

Advanced Science, EarlyView.
Magnetically induced microstructural rearrangements in ultra‐soft magnetorheological elastomers modulate their viscoelasticity, enabling programmable mechanical memory. Magnetic actuation induces long‐term viscous relaxation and double‐bumping stress responses due to particle chain formation.
Ernesto Gonzalez‐Saiz, Maria Luisa Lopez‐Donaire, Lucía Gutiérrez, Kostas Danas, Daniel Garcia‐Gonzalez   +4 more
wiley   +1 more source

Studies of the mechanism of antidiuretic hormone release [PDF]

, 1977
Dahl, G., Gratzl, Manfred, Moses, A. M., Russell, J. T., Thorn, N. A.   +4 more
core  

AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists

Advanced Science, EarlyView.
De novo GLP‐1RAs can be computationally designed to exhibit extended half‐life and superior efficacy compared to Semaglutide. Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and ...
Ting Wei, Jiating Ma, Xiaochen Cui, Jiahui Lin, Zhuoqi Zheng, Liu Cheng, Taiying Cui, Xiaoqian Lin, Junjie Zhu, Xuyang Ran, Xiaokun Hong, Luke Johnston, Zhangsheng Yu, Haifeng Chen   +13 more
wiley   +1 more source

State of Cytidine 3\u27, 5\u27 Cyclic Monophosphate (Cyclic CMP) Research [PDF]

, 1981
Murphy, Bruce E., Stone, Joseph E.
core   +1 more source

Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor

Advanced Science, EarlyView.
Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao, Weiwen Fan, Jiaqi Liu, Fangzhou Yang, Wenkai Li, Lulu Li, Zhichao Shi, Qinyuan Li, Zigao Yuan, Yuyang Jiang, Bizhu Chu   +10 more
wiley   +1 more source