Results 31 to 40 of about 1,140,604 (331)
Activation of hormone-sensitive lipase in extracts of adipose tissue
Journal of Lipid Research, 1970 Rat adipose tissue was homogenized in 0.154 m KCI, and the supernatant fluid, obtained after centrifugation at 15,000 g, was extracted with benzene to remove triglycerides. Most of the lipase activity in the extracted fluid was precipitated with ammonium
SU-CHEN TSAI +2 more
doaj +1 more source
Ultrasonics SonochemistryThe United Nations’ Sustainable Development Goals (SDGs) are significant in guiding modern scientific research. In recent years, scholars have paid much attention to MOFs materials as green materials.
Zhiwei Liu +8 more
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Short PDE4 Isoforms as Drug Targets in Disease
Frontiers in Bioscience-Landmark, 2023 The second messenger, cyclic adenosine monophosphate (cAMP), is a master regulator of signal transduction that maintains cell homeostasis. A fine balance between cAMP synthesis by adenylyl cyclase and degradation by phosphodiesterases (PDEs) underpins ...
Elka Kyurkchieva, George S. Baillie
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c-di-AMP: An essential molecule in the signaling pathways that regulate the viability and virulence of gram-positive bacteria [PDF]
, 2017 Signal transduction pathways enable organisms to monitor their external environment and adjust gene regulation to appropriately modify their cellular processes.
Cho, Kyu Hong +2 more
core +2 more sources
The Role of Cyclic AMP Signaling in Cardiac Fibrosis
Cells, 2019 Myocardial stress and injury invariably promote remodeling of the cardiac tissue, which is associated with cardiomyocyte death and development of fibrosis. The fibrotic process is initially triggered by the differentiation of resident cardiac fibroblasts
Marion Delaunay +3 more
doaj +1 more source
Current Opinion in Microbiology, 2014 Highlights • E. coli cyclic-AMP receptor protein (CRP) is a paradigm of gene regulation.• Comparison of CRPs reveals differences in their affinity of cAMP.• A range of dependency on cAMP for DNA-binding exists.• CRPs have adapted to function in the ...
Jeffrey Green +6 more
semanticscholar +1 more source
Annals of Surgery, 1976 Cyclic AMP is believed to be the intracellular agent which mediates the action of many hormones on their target cell. The mechanisms by which the nucleotide controls glycogen metabolism in liver and skeletal muscle seem to be firmly established. Data relevant to this area of research are selectively reviewed.
openaire +3 more sources
Cyclic AMP activates Ras [PDF]
Oncogene, 2000 In addition to protein kinase A (PKA), cAMP regulates the activity of cAMP-gated channels and Rap1-specific guanine nucleotide exchange factors. We tested the hypothesis that the targets of cAMP might also include regulators of the Ras protooncogene. In rat thyroid cells, thyrotropin (TSH) stimulates proliferation through a cAMP-mediated pathway that ...
O M, Tsygankova +3 more
openaire +2 more sources
Control of endogenous triglyceride breakdown in the mouse diaphragm.
Journal of Lipid Research, 1980 The control of endogenous triglyceride breakdown was studied in vitro, in the incubated intact mouse diaphragm. Isoproterenol (2 microgram/ml) produced parallel increases in glycerol and free fatty acid release, and in tissue cyclic AMP levels ...
N A Abumrad, H M Tepperman, J Tepperman
doaj +1 more source
Activation of STING Based on Its Structural Features
Frontiers in Immunology, 2022 The cGAS-cGAMP-STING pathway is an important innate immune signaling cascade responsible for the sensing of abnormal cytosolic double-stranded DNA (dsDNA), which is a hallmark of infection or cancers.
Behzad Hussain +8 more
doaj +1 more source