Results 81 to 90 of about 972,099 (307)
Second messenger systems underlying amine and peptide actions on cardiac muscle in the horseshoe crab, Limulus polyphemus [PDF]
, 1989 The biochemical mechanisms by which octopamine, catecholamines and the peptide proctolin exert their actions on Limulus cardiac muscle were investigated.
Groome, J. R., Watson, Winsor H., III
core +2 more sources
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
(Z)-2-(2-Oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide
Acta Crystallographica Section E, 2012 In the title compound, C15H12N4OS, the dihedral angle between the nine-membered indolin-2-one ring system and the phenyl ring is 2.72 (7)°.
Amna Qasem Ali +4 more
doaj +1 more source
Effects of Cyclic Amp and Dibutyryl Cyclic Amp on the Heart and Coronary Circulation
Japanese Journal of Pharmacology, 1974 Using the canine heart-lung preparation supported by a donor dog and the isolated right and left atrial preparations of the guinea-pig and the rat, the cardiac actions of dibutyryl cyclic AMP were studied and compared with those of cyclic. AMP. Dibutyryl cyclic AMP produced positive isotropic and chronotropic effects associated with an increase in the ...
Yumi Katano +4 more
openaire +4 more sources
Targeting protein–protein interactions within the cyclic AMP signaling system as a therapeutic strategy for cardiovascular disease [PDF]
, 2013 The cAMP signaling system can trigger precise physiological cellular responses that depend on the fidelity of many protein–protein interactions, which act to bring together signaling intermediates at defined locations within cells.
Brunton +8 more
core +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Bayes-Optimal Convolutional AMP [PDF]
arXiv, 2021 To improve the convergence property of approximate message-passing (AMP), convolutional AMP (CAMP) has been proposed. CAMP replaces the Onsager correction in AMP with a convolution of messages in all preceding iterations while it uses the same low-complexity matched filter (MF) as AMP.
arxiv
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Mediators of Inflammation, 2001 Aims: Phosphodiesterase 4 (PDE4) inhibitors have been described as potent anti-inflammatory compounds, involving an increase in intracellular levels of cyclic 3',5'-adenosine monophosphate (AMP).
Noëlla Germain +4 more
doaj +1 more source
Acta Societatis Botanicorum Poloniae, 2014 A fluorescence-detection HPLC procedure has been applied to identify and quantify acridine orange in lichen samples. The dye accumulates in thalli of the lichen Usnea aurantiaco-atra and, in part, it is recovered from protamine-precipitated nucleic acids
C. Vicente +3 more
doaj +1 more source