Results 81 to 90 of about 233,579 (364)
Disinhibition of hippocampal CA3 neurons induced by suppression of an adenosine A1 receptor-mediated inhibitory tonus: Pre- and postsynaptic components [PDF]
Intracellular recordings were performed on hippocampal CA3 neuronsin vitro to investigate the inhibitory tonus generated by endogenously produced adenosine in this brain region.
Alzheimer+60 more
core +1 more source
W‐Based Thin Film Metallic Glasses Doped with Ni, Zr, and B for Industrial Applications
This work is the first to deal with a comprehensive comparison of two metallic glass systems, W–Zr–B and W–Ni–B, in terms of their suitability for specific industrial applications. Their mechanical and tribological properties are compared and discussed in combination with structural homogeneity on different types of technically relevant substrates and ...
Zbynek Studeny+5 more
wiley +1 more source
Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells. [PDF]
Treatment of mouse lymphoma S49 cells with D,L-alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, depleted cellular polyamine levels and stopped cell growth. The cells were arrested predominantly in G1.
Coffino, P, Marton, LJ, McConlogue, LC
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Galectin-12 in Cellular Differentiation, Apoptosis and Polarization. [PDF]
Galectin-12 is a member of a family of mammalian lectins characterized by their affinity for β-galactosides and consensus amino acid sequences. The protein structure consists of a single polypeptide chain containing two carbohydrate-recognition domains ...
Liu, Fu-Tong, Wan, Lei, Yang, Ri-Yao
core +2 more sources
This study designs Ta–Mo–Cr–Ti–Al refractory high‐entropy alloys with a disordered body‐centered‐cubic A2 crystal structure aiming for improved ductility, lower density, and oxidation resistance. Four alloy compositions are identified by thermodynamic calculations.
Kateryna Khanchych+7 more
wiley +1 more source
Toughness of Confined Auxetic Foams
Auxetic (negative Poisson's ratio) materials offer benefits such as impact mitigation, thermal insulation, vibration damping, and reduced shear strain, although their fracture mechanics are largely unexplored. This study investigates damage initiation and propagation in confined re‐entrant auxetic foams from polyurethane via experimental ...
Adrianos E. F. Athanasiadis+3 more
wiley +1 more source
Fe‐ and Mn‐containing AlSi alloys undergo aluminothermic reaction with Mn oxide in sessile‐drop and crucible experiments forming poor‐wetting Al2O3 while Mn enriches in the alloy. Primary Fe‐containing particles are preferentially attached to the Mn oxide.
Hanka Becker+6 more
wiley +1 more source
A simulative evaluation of triply periodic minimal surface (TPMS) structures for an elastocaloric application under compressive load is performed. For the evaluation of the structure's performance, surface/volume ratio, generated heat and invested mechanical work are taken into account and are compared to a tube as a reference specimen.
Michael Fries+3 more
wiley +1 more source
Genome-Wide Mapping Defines a Role for C/EBPβ and c-Jun in Non-Canonical Cyclic AMP Signalling
The novel exchange protein activated by cyclic AMP (EPAC1) activator, I942, induces expression of the suppressor of cytokine signalling 3 (SOCS3) gene, thereby inhibiting interleukin 6 (IL6) inflammatory processes in human umbilical vein endothelial ...
Jolanta Wiejak+3 more
doaj +1 more source
Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3,5-monophosphate. [PDF]
In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response to changes in light conditions and to an endogenous circadian rhythm.
BURNSIDE, Beth+3 more
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