Cofactor Fingerprinting with STD NMR to Characterize Proteins of Unknown Function: Identification of a Rare cCMP Cofactor Preference [PDF]
Proteomics efforts have created a need for better strategies to functionally categorize newly discovered proteins. To this end, we have employed saturation transfer difference NMR with pools of closely related cofactors, to determine cofactor preferences.
Sem, Daniel, Yao, Huili
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Protein kinase a distribution differentiates human glioblastoma from brain tissue [PDF]
Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to ...
Caretta, Antonio +3 more
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Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides
Background: Cyclic dinucleotides (cyclic di-guanosine monophosphate (c-di-GMP) and cyclic di-adenosine monophosphate (c-di-AMP)) and lipopolysaccharides (LPS) are pathogen-associated molecular patterns (PAMPs).
Samira Elmanfi +5 more
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Influence of Platelet Aggregation Modulators on Cyclic AMP Production in Human Thrombocytes
Background: Cyclic AMP is a powerful inhibitor of platelet aggregation. In the present study we examined the effect of platelet aggregation modulators on cyclic AMP content in human thrombocytes.
Boyanov Krasimir O., Maneva Ana I.
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How to rewire the host cell: A home improvement guide for intracellular bacteria. [PDF]
Intracellular bacterial pathogens have developed versatile strategies to generate niches inside the eukaryotic cells that allow them to survive and proliferate.
Cornejo, Elias +2 more
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6-Bromo-2-methylsulfanyl-1,3-benzothiazole
The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS ...
Michał A. Dobrowolski +2 more
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Pentacarbonyl(imidazolidine-2-thione-κS)tungsten(0)
In the title complex, [W(C3H6N2S)(CO)5], the W atom displays an octahedral coordination with five CO molecules and an imidazolidine-2-thione molecule. The W(CO)5 unit is coordinated by the cyclic thione ligand through a W—S dative bond.
Salah Merniz +4 more
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Continuous growth of proximal tubular kidney epithelial cells in hormone-supplemented serum-free medium. [PDF]
An epithelial cell line from pig kidney (LLC-PK1) with properties of proximal tubular cells can be maintained indefinitely in hormone-supplemented serum-free medium. Continuous growth requires the presence of seven factors: transferrin, insulin, selenium,
Chuman, L +3 more
core
Cell Sorting daring Pattern Formation in Dictyostelium [PDF]
Formation of the prestalk-prespore pattern in Dictyostelium was investigated in slugs and submerged clumps of cells. Prestalk and prespore cells were identified by staining with vital dyes, which are shown to be stable cell markers.
David, Charles N., Sternfeld, John
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Estrogenic Compounds or Adiponectin Inhibit Cyclic AMP Response to Human Luteinizing Hormone in Mouse Leydig Tumor Cells [PDF]
Thi Mong Diep Nguyen +2 more
openalex +1 more source

