Results 91 to 100 of about 131,836 (300)

An enzymatic mechanism for calcium current inactivation in dialysed Helix neurones

, 1986
'Wash-out' and inactivation of the Ca current were examined in dialysed, voltage-clamped neurones of Helix aspersa under conditions that isolate the Ca current virtually free of other currents. EGTA or other internal Ca2+ chelators were routinely omitted
Chad, J.E., Eckert, R.
core  

Synthesis of stereochemically diverse cyclic analogs of tubulysins

, 2018
The synthesis of tubulysin analogs containing stereochemically diverse cyclic Tuv moieties is described. A tetrahydropyranyl moiety was incorporated into the Tuv unit by enantioselective hetero Diels-Alder reactions of Danishefsky's diene ...
류재상
core   +1 more source

Fatty acid oxidation and esterification in isolated rat hepatocytes: regulation by dibutyryl adenosine 3′,5′-cyclic monophosphate

Journal of Lipid Research, 1973
Isolated rat hepatocytes rapidly utilized [14C] palmitate and, in particular, synthesized large amounts of neutral lipids from palmitate. Incorporation into cellular lipids occurred at a linear rate proportional to the medium concentration of fatty acids.
Charles J. Homcy, Simeon Margolis
doaj   +1 more source

Creep‐Induced Microstructural Evolution in an A2‐B2 Superalloy

Advanced Engineering Materials, EarlyView.
A 27.3Ta‐27.3Mo‐27.3Ti‐8Cr‐10Al (at.%) refractory high‐entropy alloy with precipitation‐strengthened A2‐B2 microstructure was studied by creep tests at 1030°C, which demonstrate a transition in deformation mechanisms in the range of 100–150 MPa applied stress. This is associated with changes in dislocation–precipitate interactions. Relevant deformation
Liu Yang, Aparajita Pramanik, Sandipan Sen, Shubhashis Dixit, Marcel Muench, R. J. Vikram, Daniel Schliephake, Yolita M. Eggeler, Ankur Chauhan, Martin Heilmaier, Alexander Kauffmann   +10 more
wiley   +1 more source

Influence of Test Temperature and Test Frequency on Fatigue Life of Aluminum Alloy EN AW‐2618A

Advanced Engineering Materials, EarlyView.
The influence of test temperature and test frequency on the fatigue life of EN AW‐2618A is investigated. High‐cycle fatigue tests are performed at different test temperatures and frequencies on the 1000 h/230°C overaged state. Both test parameters reduce fatigue life due to time‐dependent damage mechanisms.
Ying Han, Julian M. Rosalie, Jan Radners, Mauro Madia, Philipp von Hartrott, Birgit Skrotzki   +5 more
wiley   +1 more source

Influence of Platelet Aggregation Modulators on Cyclic AMP Production in Human Thrombocytes

Folia Medica, 2018
Background: Cyclic AMP is a powerful inhibitor of platelet aggregation. In the present study we examined the effect of platelet aggregation modulators on cyclic AMP content in human thrombocytes.
Boyanov Krasimir O., Maneva Ana I.
doaj   +1 more source

High‐Temperature Nanoindentation of Metals: Assessing Thermal Drift, Frame Compliance, and Chemical Composition Effects on the Reported Mechanical Properties

Advanced Engineering Materials, EarlyView.
Do not let thermal drift and instrument artifacts deceive high‐temperature nanoindentation results. We compare classical Oliver–Pharr and automatic image recognition analyses across steels and a Ni alloy to quantify these effects. Accounting for artifacts reveals systematic softening with temperature, while Cr and Ni additions boost resistance ...
Velislava Yonkova, Steffen Brinckmann, Ruth Schwaiger   +2 more
wiley   +1 more source

Synergistic growth stimulation of Conn’s adenoma cells by cyclic AMP and GMP

, 1979
Synergistic growth stimulation of Conn’s adenoma cells by cyclic AMP and GMP in primary ...
L. MENGATO, E. DRAGHI, P. G. ANDREIS, ARMATO, Ubaldo   +3 more
core  

Ga and Gß Proteins Regulate the Cyclic AMP Pathway That Is Required for Development and Pathogenicity of the Phytopathogen Mycosphaerella graminicola

, 2009
We identified and functionally characterized genes encoding three G alpha proteins and one G beta protein in the dimorphic fungal wheat pathogen Mycosphaerella graminicola, which we designated MgGpa1, MgGpa2, MgGpa3, and MgGpb1, respectively.
Lee, T.A.J., van der, Wit, P.J.G.M., de, Kema, G.H.J., M'Barek, S., Ben, Waalwijk, C., Mehrabi, A.   +5 more
core   +1 more source

The retinitis pigmentosa mutation c.3444+1G>A in CNGB1 results in skipping of exon 32 [PDF]

, 2010
Retinitis pigmentosa (RP) is a severe hereditary eye disorder characterized by progressive degeneration of photoreceptors and subsequent loss of vision. Two of the RP associated mutations were found in the CNGB1 gene that encodes the B subunit of the rod
Biel Martin, Hennel, Roman, Biel, Martin, Hammelmann, Verena, Michalakis, Stylianos, Elvir Becirovic, Roman Hennel, Kostadinka Nakova, Hennel Roman, Becirovic Elvir, Hammelmann Verena, Becirovic, Elvir; https://orcid.org/, Nakova, Kostadinka, Nakova Kostadinka, Martin Biel, Stylianos Michalakis, Michalakis Stylianos, Becirovic, Elvir, Verena Hammelmann   +18 more
core   +1 more source