Surgical removal of visceral adipose tissue has therapeutic benefit in male APP<sup>NL-F</sup> mice. [PDF]
McFadden SA +8 more
europepmc +1 more source
Cyclic AMP-dependent regulation of ryanodine receptors in healthy and diseased hearts. [PDF]
Hulsurkar MM +5 more
europepmc +1 more source
The cGAS-STING signaling pathway as a therapeutic target in human diseases. [PDF]
Xiao Y +6 more
europepmc +1 more source
Rab2A modulates liver fibroblast growth factor 21 (FGF21) expression and systemic metabolism via apolipoprotein B-CREBH signaling. [PDF]
Chen ZY, Xu M, Chen S, Chen L.
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Polynucleotides Enhance Collagen Synthesis via Modulating Phosphoenolpyruvate Carboxykinase 1 in Senescent Macrophages: Experimental Evidence. [PDF]
Byun KA, Park HJ, Oh S, Son KH, Byun K.
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Short- and long-term effects of single neonatal exposure to propofol anesthesia on cognitive function. [PDF]
Liu S +11 more
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Cyclic AMP response element-binding protein and depression
Expert Review of Neurotherapeutics, 2002Depression is one of the most common and most devastating psychiatric disorders. Although a variety of treatment strategies is available, a major problem in its therapy consists of the unpredictability of the drug response. Furthermore, most antidepressant drugs, which usually increase 5-HT and norepinephrine levels in the synaptic cleft, are likely to
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Cyclic AMP‐Responsive Element Binding Protein in Brain Mitochondria
Journal of Neurochemistry, 1999Abstract: Cyclic AMP‐responsive element binding protein (CREB) is critically involved in many important brain functions, including the formation of long‐term memory. CREB is the best characterized member of a family of transcription factors (CREB/ATF family) recognized to be important nuclear targets for intracellular signal transduction systems. Here
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Presence of a Cyclic AMP Response Element‐Binding Protein in Oligodendrocytes
Journal of Neurochemistry, 1993Abstract: Several lines of evidence indicate that cyclic AMP (cAMP) induces oligodendrocyte differentiation. However, the mechanism(s) of this stimulation remains unknown. Because in several cell types the transcriptional activity of various cAMP‐responsive genes is regulated through a cisacting DNA sequence known as cAMP response element (CRE), we ...
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