Results 141 to 150 of about 32,383 (302)
Neuropsychiatric Disease and Treatment, 2016 Xu Liu,1,2,* Haibiao Guo,1,* Mohammad Daud SOM Sayed,3,4,* Yang Lu,3,4,* Ting Yang,5,* Dongsheng Zhou,6 Zhongming Chen,6 Haitao Wang,1 Chuang Wang,3,4 Jiangping Xu1 1Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical ...
Liu X +9 more
doaj
Dielectric Elastomer Actuators as Safe and Effective Tools for Mechanostimulation of Human Cells
Advanced Intelligent Systems, EarlyView.Replicating physiological forces is crucial for realistic cell models. Dielectric elastomer actuators (DEAs) offer a soft alternative, though their high voltages raised toxicity concerns. We demonstrate that DEA stimulation causes no cell damage, cell death or cell‐cycle disruption, while activating mechanosensitive responses.
Simon Holzer +6 more
wiley +1 more source
, 2006 Depression is the major psychiatric ailment of our times, afflicting ~20% of the population. Despite its prevalence, the pathophysiology of this complex disorder is not well understood. In addition, although antidepressants have been in existence for the
Nair, A., Vaidya, V. A.
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Advanced NanoBiomed Research, EarlyView.Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro +3 more
wiley +1 more source
, 1994 The promoter activity of 1432 bp upstream of the human prostaglandin-endoperoxide synthase 2 gene (PTGS2) was examined in differentiated U937 monocytic cells expressing prostaglandin-endoperoxide synthase 2 mRNA.
Inoue, Hiroyasu +9 more
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Advanced NanoBiomed Research, EarlyView.Platelet membrane‐coated layered double hydroxide nanoparticles were engineered to target inflamed endothelium at early‐stage atherosclerosis and enhance therapeutic efficacy. The biomimetic platform improves stability, immune escape, and inflamed vascular cell targeting, resulting in reduced oxidative stress and downregulated adhesion molecules.
Xiuwen Zhang +4 more
wiley +1 more source
Expression of corticotrophin-releasing hormone receptor subtypes in human myometrium and cloning of the promoter region for the CRH receptors type 2 [PDF]
Corticotrophin releasing hormone (CRH) and CRH receptor (CRH-R) appear to play a number of important roles in human pregnancy. The purpose of the first part of my project was to clone and sequence CRH-R subtypes from human myometrial biopsies.
Chen, Jing
core
Cyclic AMP Receptor Protein−Aequorin Molecular Switch for Cyclic AMP
, 2011 Molecular switches are designer molecules that combine the functionality of two individual proteins into one, capable of manifesting an "on/off" signal in response to a stimulus.
C. Mark Ensor +9 more
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Nicotine as an odorant : a biochemical and electrophysiological study of receptors for nicotine in the olfactory epithelium of the rat [PDF]
The results suggest that nicotine vapour stimulates an in vitro olfactory preparation in three strains of rat and two strains of mouse, in a manner similar to known odorants.
Edwards, Damian Andrew
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Angewandte Chemie International Edition, EarlyView.Electroenzymatic CO2 fixation enables energy‐efficient, highly selective synthesis of complex molecules. Unlocking its full potential requires fundamental understanding of electrode‐coupled reductases and carboxylases. This review critically discusses available enzymes, product scope, and key thermodynamic and kinetic considerations, highlighting ...
Leonardo Castañeda‐Losada +4 more
wiley +1 more source