Results 191 to 200 of about 29,900 (296)

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim   +4 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

open access: yesExploration, EarlyView.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao   +11 more
wiley   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

open access: yesFood Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang   +5 more
wiley   +1 more source

Pulicaria incisa Infusion Modulates the Gut Microbiota and Improves Locomotor Activity and Exploratory Behavior in Aging Mice

open access: yesFood Frontiers, EarlyView.
‐Pi infusion significantly improved locomotor activity and exploratory behavior in aging mice; its bioactive compounds may have direct effects on behavior, which may be accompanied by a putative indirect effect involving the gut microbiota. ‐Pi infusion consumption restored commensal Bacilli levels and caused a significant decrease in Clostridia levels
Yulia Kroupitski   +7 more
wiley   +1 more source

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