Dynamic control of bacterial antiphage defense through the CdnG-Cap5 cyclic oligonucleotide-based antiphage pathway in Vibrio cholerae. [PDF]
Ye F +6 more
europepmc +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
cGAS-STING signaling: a therapeutic target in inflammatory bowel disease and related colorectal cancer. [PDF]
Chen X, Tang X, Chen S, Ye Y, Mao F.
europepmc +1 more source
Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs +5 more
wiley +1 more source
Isoquercitrin induces melanogenesis in B16F10 melanoma cells and zebrafish via the p38 and PKA/CREB signaling pathways: an experimental study. [PDF]
Lee JH, Ko YS, Eom YS, Kim SJ.
europepmc +1 more source
SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi +14 more
wiley +1 more source
Follicle-Stimulating Hormone in Peripheral Metabolism: Novel Insights into Growth Regulation and Potential Applications in Boar Production. [PDF]
Wang G, Han X, Wu, Zhuo Y.
europepmc +1 more source
Cell-Type-specific Regulation of Nerve Growth Factor (NGF) Synthesis in Non-neuronal Cells [PDF]
Matsuoka, Ichiro +2 more
core
The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
Shikonin improves intestinal barrier function through modulation of GPX4 expression in intestinal epithelial cells. [PDF]
Yang F +6 more
europepmc +1 more source

