Results 91 to 100 of about 20,015 (278)

Effect of sand gradation and fines type on the liquefaction behaviour of sand-fines mixtures [PDF]

open access: yes, 1996
Equivalent granular void ratio and equivalent granular steady state line was used as the common basis for synthesizing test results. In isolating the influence of host sand, two sand-fines mixes with different host sand, but the same fines type and ...
Rahman, M.M., Lo, S.R.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

A simple permanent deformation model of rockfill materials

open access: yesWater Science and Engineering, 2018
Existing experimental results have shown that using a semi-log linear relationship between the permanent volumetric strain and cyclic number underestimates the volumetric deformation of rockfill materials with a large cyclic number, and that the error ...
De-gao Zou   +4 more
doaj   +1 more source

Experimental study of strain accumulation of silica sand in a cyclic triaxial test [PDF]

open access: yes, 2014
The experimental and phenomenological investigation of the elasto-plastic long-term behaviour of soils under dynamic loading is important for the development of risk analysis tools and numerical accumulation models for settlement prediction.
Benoot, Jelle   +2 more
core  

Nucleation in sheared granular matter

open access: yes, 2017
We present an experiment on crystallization of packings of macroscopic granular spheres. This system is often considered to be a model for thermally driven atomic or colloidal systems.
Radin, Charles   +3 more
core   +1 more source

Dilatancy relation for overconsolidated clay [PDF]

open access: yes, 2017
A distinct feature of overconsolidated (OC) clays is that their dilatancy behavior is dependent on the degree of overconsolidation. Typically, a heavily OC clay shows volume expansion, whereas a lightly OC clay exhibits volume contraction when subjected ...
Gao, Zhiwei, Yin, Zhen-Yu, Zhao, Jidong
core   +2 more sources

Effect of confining pressure on ballast degradation and deformation under cyclic triaxial loading

open access: yesGéotechnique, 2007
Traditional railway foundations or substructures have become increasingly overloaded in recent years, owing to the introduction of faster and heavier trains. A lack of substructure re-engineering has resulted in maintenance cycles becoming more frequent and increasingly expensive.
Lackenby, J.   +3 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Triaxial compressive failure of thermally damaged granite following low- and high-cycle fatigue loading

open access: yesResults in Engineering
This paper investigated the triaxial compressive characteristics of thermally damaged granite following cyclic loading. Thermal treatments at various high temperatures (200.0 °C, 400.0 °C, 500.0 °C, and 600.0 °C) were performed on granite.
B. Qiu, Z. Wang, X. Zhao, L.F. Fan
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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