Results 171 to 180 of about 439,193 (238)
Mitochondrial respiration and characteristics of skeletal muscles in children with cerebral palsy
Developmental Medicine &Child Neurology, EarlyView.Skeletal muscles utilize numerous mitochondria for energy production needed during muscle contraction. Mitochondria produce this energy through the electron transport chain. After an injury such as ACL‐injury in typically developing children, there is a reduction in muscle mitochondrial respiration and content.
Sudarshan Dayanidhi +10 more
wiley +1 more source
Supramolecular polymer formation by cyclic dinucleotides and intercalators affects dinucleotide enzymatic processing. [PDF]
Future Sci OA, 2016 Nakayama S +4 more
europepmc +1 more source
Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou +5 more
wiley +1 more source
Adopting STING agonist cyclic dinucleotides as a potential adjuvant for SARS-CoV-2 vaccine
, 2020 Wu J, Chen Y, Li Y.
europepmc +1 more source
Intestinal STING‐(Over)activation—A Contributing Factor to Food Allergies?
Allergy, EarlyView.
Sophie Goebel, Hannah Ruth Schiller
wiley +1 more source
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Cyclic dinucleotides (CDNs) reversed T cells tolerance in anti-tumor immunotherapy [PDF]
J Immunother Cancer, 2015 Fu J +10 more
europepmc +1 more source
The FEBS Journal, EarlyView.Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti +8 more
wiley +1 more source
Ligand binding represses bacterial histidine kinase activity by inhibiting its dimerization
The FEBS Journal, EarlyView.PdtaS is a kinase in the pathogen Mycobacterium tuberculosis that senses copper and nitric oxide and controls virulence gene expression, but how the kinase senses these compounds was unclear. We show that PdtaS is active as a dimer with each monomer phosphorylating the other in trans.
Gaurav D. Sankhe +6 more
wiley +1 more source
Cyclic dinucleotides (CDNs) anti-tumors response by activating DC and NK cell crosstalk [PDF]
J Immunother Cancer, 2014 Fu J, Pardoll D, Kim Y.
europepmc +1 more source