Results 111 to 120 of about 8,341 (207)

Flipping the Card With Enantiodivergent Organocatalysis

open access: yesChemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre   +3 more
wiley   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1877-1903, August 2026.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 8, August 2026.
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng   +9 more
wiley   +1 more source

Towards Bio‐Based Benzoxazines (2015–2025): A Critical Review of Renewable Building Blocks, Formaldehyde‐Free Aldehydes, and ECHA Hazard Landscape

open access: yesPolymers for Advanced Technologies, Volume 37, Issue 8, August 2026.
ABSTRACT This review provides a critical overview of research on fully bio‐based benzoxazines over the period 2015–2025. A bibliometric analysis based on the Web of Science database is used to map how the field has evolved and to identify the renewable building blocks that have been most widely adopted.
Elizabeth Alvarez Perez, Alice Mija
wiley   +1 more source

Vibrio Community Structure Shapes the Diversity of Carbenicillin‐Hydrolysing Class A β‐Lactamase Circulating in European Coastal Environments

open access: yesEnvironmental Microbiology, Volume 28, Issue 8, August 2026.
Vibrio communities shape carbenicillinase diversity in European coasts. Sediments serve as reservoirs of antibiotic‐resistant Vibrio alginolyticus, which can move into the water column and accumulate in bivalves. This spreads β‐lactamase resistance and raises human exposure risks to antibiotic‐resistant pathogenic Vibrio, especially as higher seawater ...
Berenice Reggiardo   +23 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

open access: yesCell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao   +7 more
wiley   +1 more source

Strigolactone‐mediated architecture regulation and stress resilience: Insights and innovations for crop breeding

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 8, Page 2548-2576, August 2026.
This review summarizes the discovery, biosynthesis, and transport of strigolactone, and the D14‐D3/MAX2‐D53/SMXLs signaling module. It highlights diverse roles of strigolactone in plant architecture, stress responses, and crop breeding, including species‐specific functions, hormonal crosstalk, and agricultural applications.
Qingliang Hu, Jiayang Li, Bing Wang
wiley   +1 more source

Physiology and Transcriptomics Reveal Divergent Strategies of Mycorrhiza‐Mediated Drought Adaptation in Poplar

open access: yesPlant, Cell &Environment, Volume 49, Issue 8, Page 5078-5094, August 2026.
ABSTRACT Mycorrhizal symbiosis shapes plant growth and stress resilience. Here, we compared physiological and molecular responses of poplars (P. x canescens) colonised by Paxillus involutus (Pi) or Cenococcum geophilum (Cg) under control conditions, drought stress and recovery.
Huili Shi, Zhuchou Lu, Andrea Polle
wiley   +1 more source

Carnosine‐Related Metabolism in Rat Cardiomyocytes and Human Heart Tissue

open access: yesThe FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Carnosine‐related metabolism in rat cardiomyocytes and human heart tissue. Jade V Creighton, Lívia de Souza Gonçalves, Saulo Gil, Bianca Scigliano Vargas, Leonardo Jensen, Marisa Helena Gennari de Medeiros, Hamilton Roschel, Mark D Turner, Craig L Doig, Guilherme Giannini Artioli, Craig Sale.
Jade V. Creighton   +10 more
wiley   +1 more source

The Role of Gut Microbiota in Liver Regeneration After Partial Hepatectomy: New Evidence From Animal and Human Studies

open access: yesThe FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Partial hepatectomy (PH) reshapes gut microbiota composition, resulting in the release of microbial metabolites and components, including short chain fatty acids (SCFAs)/β‐hydroxybutyric acid (BHB), bacterial DNA and extracellular vesicles (EVs), bile acids (deoxycholic acid, DCA), and aminobenzoate degradation products.
Roberto Loi   +3 more
wiley   +1 more source

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