Results 131 to 140 of about 863,677 (247)

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, Volume 4, Issue 3, September 2026.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Metal‐Free Decarboxylative Allylation of N‐Protected Amino Acids and Carboxylic Acids via Thioxanthone Photocatalysis

ChemCatChem, Volume 18, Issue 17, 14 September 2026.
A mild, metal‐free photochemical decarboxylative allylic alkylation protocol using inexpensive thioxanthone under blue LEDs couples diverse carboxylic and N‐protected amino acids with Morita–Baylis–Hillman derivatives, offering broad substrate scope and a mechanism supported by radical‐trapping experiments.
Areti N. Karamitrou, Olga G. Mountanea, Manos V. G. Lantzanakis, Christoforos G. Kokotos   +3 more
wiley   +1 more source

Bioactive Peptides From the Cucurbitaceae Family: From Identification and Health‐Promoting Functions to Industrial Utilization

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
From fruit to function: Cucurbitaceae‐derived peptide production, bioactive potential screening and industrial applications. ABSTRACT Cucurbitaceae is a major plant family within the kingdom Plantae, encompassing popular food crops such as zucchini, squash, pumpkins, and melons.
Himani R. Kekiri Obada Gamage, Mahya Bahmani, Utpal Bose, Mekhala Vithana, Michelle L. Colgrave, Angéla Juhász   +5 more
wiley   +1 more source

A Sustainable Approach for the Use of Plant Proteins as Functional Ingredients in Dairy Alternatives

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Plant proteins in dairy alternatives. ABSTRACT The increasing global demand for sustainable and health‐promoting foods has positioned plant‐based proteins as key components in the development of dairy alternatives. This review critically examines plant protein sources: legumes, cereals, pseudocereals, oilseeds, and nuts not merely by composition, but ...
Boutheina Ben Akacha, Monika Michalak, Miroslava Kačániová, Maciej Ireneusz Kluz, Wirginia Kukula‐Koch, Wojciech Koch, Ramona Suharoschi, Rania Ben Saad, Stefania Garzoli, Anis Ben Hsouna   +9 more
wiley   +1 more source

Modulation of Staphylococcus epidermidis (RP62A) extracellular polymeric layer by marine cyclic dipeptide-cyclo(l-leucyl-l-prolyl) thwarts biofilm formation.

Biochimica et Biophysica Acta - Biomembranes, 2017
S. Gowrishankar, S. K. Pandian
semanticscholar   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, Volume 73, Issue 9, Page 1251-1261, September 2026.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source

Neural Stem Cell‐Derived Extracellular Vesicles Improve CNS Delivery and Therapeutic Efficacy of Antisense Oligonucleotide in Amyotrophic Lateral Sclerosis

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Passive ASO association with NSC‐EVs enhances neuronal uptake and CNS accumulation. NSC‐EV‐ASOs suppress pathogenic targets in ALS cellular models and, following intranasal administration, delay disease onset and improve motor function in SOD1‐G93A mice. These findings provide proof‐of‐concept evidence supporting NSC‐EVs as a platform for enhancing CNS
Yaochao Zheng, Taylor Jade Ellison, Robert Garrard, Jinghui Gao, Xinning Lai, Lin Lan, Jin Xie, Jie Jiang, Yao Yao   +8 more
wiley   +1 more source

Cyclic dipeptide cyclo(l-leucyl-l-prolyl) from marine Bacillus amyloliquefaciens mitigates biofilm formation and virulence in Listeria monocytogenes.

Pathogens and Disease, 2016
S. Gowrishankar, M. Sivaranjani, A. Kamaladevi, A. V. Ravi, K. Balamurugan, Shunmugiah Karutha Pandian   +5 more
semanticscholar   +1 more source

Improving Proteolysis‐Targeting Chimera Delivery by Targeting Key Biomarkers in Tumor Endocytosis Pathways

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen, Jiayan Jiao, Huiling Yang, Tao He   +3 more
wiley   +1 more source