Results 51 to 60 of about 18,412 (234)

Evolutionary radiation of lanthipeptides in marine cyanobacteria [PDF]

, 2018
Lanthipeptides are ribosomally derived peptide secondary metabolites that undergo extensive posttranslational modification. Prochlorosins are a group of lanthipeptides produced by certain strains of the ubiquitous marine picocyanobacteria Prochlorococcus
Becker, Jamie William, Berta-Thompson, Jessica Weidemier, Chisholm, Sallie W, Cubillos, Andres Fernando, van der Donk, Wilfred A.   +4 more
core   +1 more source

Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]

Zhongguo niangzao
In this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
doaj   +1 more source

Champacyclin, a New Cyclic Octapeptide from Streptomyces Strain C42 Isolated from the Baltic Sea [PDF]

, 2013
New isolates of Streptomyces champavatii were isolated from marine sediments of the Gotland Deep (Baltic Sea), from the Urania Basin (Eastern Mediterranean), and from the Kiel Bight (Baltic Sea).
Baumann, Heike Irmgard, Ensle, Paul, Imhoff, Johannes F., Kleinschmidt, Katrin, Pesic, Alexander, Süssmuth, Roderich, Wiese, Jutta   +6 more
core   +2 more sources

A minimalistic hydrolase based on co-assembled cyclic dipeptides [PDF]

Organic & Biomolecular Chemistry, 2019
Cyclic dipeptides based on proteinogenic amino acids form higher aggregates in water with an enzyme-like activity. Are they relevant for abiogenesis?
Alexander Kleinsmann, Boris Nachtsheim
openaire   +2 more sources

Poly(acrylic acid)/Dipeptide Double-Network Hydrogel to Achieve a Highly Stretchable Strain Sensor

Chemosensors, 2022
Flexible and stretchable strain sensors can be applied for human health monitoring and disease diagnoses via the output of multiple biophysical signals. However, it is still a challenge to fabricate short-peptide-based strain sensors. Here, we prepared a
Xin Luo, Boya Ding, Xingcen Liu
doaj   +1 more source

Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily. [PDF]

, 2017
Insight regarding how diverse enzymatic functions and reactions have evolved from ancestral scaffolds is fundamental to understanding chemical and evolutionary biology, and for the exploitation of enzymes for biotechnology.
Akiva, Eyal, Babbitt, Patricia C, Copp, Janine N, Tokuriki, Nobuhiko   +3 more
core   +1 more source

Cyclic dipeptides and the human microbiome: Opportunities and challenges

Bioorganic & Medicinal Chemistry, 2023
Research into the human microbiome has implicated its constituents in a variety of non-communicable diseases, with certain microbes found to promote health and others leading to dysbiosis and pathogenesis.Microbes communicate and coordinate their behaviour through the secretion of small molecules, such as cyclic dipeptides (CDPs), into their ...
Ogilvie, Charlene Elizabeth, Melo Czekster, Clarissa   +1 more
openaire   +3 more sources

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

Anti-Quorum-Sensing Activity of Tryptophan-Containing Cyclic Dipeptides

Marine Drugs, 2022
Quorum sensing (QS) can regulate the pathogenicity of bacteria and the production of some virulence factors. It is a promising target for screening to find anti-virulence agents in the coming post-antibiotics era. Cyclo (L-Trp-L-Ser), one variety of cyclic dipeptides (CDPs), isolated from a marine bacterium Rheinheimera aquimaris, exhibited anti-QS ...
Yinglu Wang, Qian Zheng, Li Li, Lile Pan, Hu Zhu   +4 more
openaire   +3 more sources

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source