Results 161 to 170 of about 4,865 (234)

Loncastuximab Tesirine in Relapsed/Refractory Diffuse Large B‐Cell Lymphoma: Evidence and Practical Guidance From Italian Clinical Experience

open access: yesEuropean Journal of Haematology, Volume 117, Issue 1, Page 144-153, July 2026.
ABSTRACT Patients with relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) who progress to the third‐line setting face a lack of standardized treatment, despite the presence of multiple available therapies. In this context, antibody–drug conjugates represent a relatively new class of anticancer agents; among them, loncastuximab tesirine is ...
Francesca Bonello   +7 more
wiley   +1 more source

Targeting miR‐124‐3p to Induce Antidepressant‐Like Effects in Female Mice: MicroRNA Modulation of Stress Resilience

open access: yesEuropean Journal of Neuroscience, Volume 64, Issue 2, July 2026.
miR‐124‐3p mimic reduced immobility in the Porsolt swim test in female mice. Proteomics revealed region‐specific changes in hippocampus, hypothalamus and PFC. Downregulation of immune and stress‐related proteins in hippocampus and hypothalamus. Upregulation of synaptic and metabolic proteins in the prefrontal cortex.
Maria A. Kuznetsova   +6 more
wiley   +1 more source

Efficacy and Safety of L‐Carnosine‐Containing Hyaluronate Injection for Facial Skin Hydration and Brightness: A Randomized, Controlled, Evaluator‐Blinded Trial

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background L‐carnosine, a dipeptide with superior antioxidant and antiglycation properties, serves as the core active component in this study. We aimed to evaluate the efficacy and safety of a novel injectable composite solution, which features L‐carnosine in combination with non‐crosslinked sodium hyaluronate, glycine, alanine, proline, and ...
Zhanhong Li   +24 more
wiley   +1 more source

An N‐acetyltransferase‐MAPK fusion protein modulates developmental reprogramming in Physcomitrium patens

open access: yesNew Phytologist, Volume 251, Issue 1, Page 321-339, July 2026.
Summary We discovered a previously uncharacterized moss‐specific protein, Rosetta NATD‐MAPK 1 (RAK1) in Physcomitrium patens, which uniquely integrates MAP kinase (MAPK)‐dependent signaling with N‐acetyltransferase activity. Through phenotypical and biochemical analyses, we characterized RAK1 function in the regulation of the 2D‐to‐3D growth transition.
Cloe de Luxán‐Hernández   +17 more
wiley   +1 more source

Space ionizing radiation triggers the formation of peptides and organophosphates on olivine surfaces. [PDF]

open access: yesNat Commun
Ding R   +9 more
europepmc   +1 more source

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