Results 141 to 150 of about 4,865 (234)

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, Volume 13, Issue 41, 22 July 2026.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source

The Chemical Regulatory Landscape of Biomolecular Condensates

Aggregate, Volume 7, Issue 7, July 2026.
Chemical regulation of biomolecular phase separation offers a unique opportunity to bridge molecular‐level chemistry with emergent cellular organization. Chemically informed strategies for controlling condensate condensates through chemically tractable parameters such as interaction valency, solvent quality, and molecular crowding provides a unifying ...
Di Liu, Xin Zhang
wiley   +1 more source

Interfacial Engineering for Perovskite Photovoltaics: Multimolecular Synergy Versus All‐In‐One Integration

Aggregate, Volume 7, Issue 7, July 2026.
Distinct from traditional single‐function regulation strategy, both multimolecule synergistic regulation and all‐in‐one integration regulation strategies can achieve multifunctional regulation. This paper presents the research progress, advantages, and limitations, as well as applicable scenarios of the two strategies, offering prospects for the future
Jin Wang, Weihui Bi, Zengyi Ma, Shen Xing, Mingyue Wang, Haijun Wang, Siyuan Xiao, Yufei Zhong   +7 more
wiley   +1 more source

Nuclear dysfunction in aging and neurodegeneration

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Neurodegenerative diseases are characterized by a loss of neuronal function and structure, often in a region‐specific manner. Multiple factors contribute to neuronal dysfunction and death, including pathogenic protein buildup, protein mislocalization, and inflammation. Despite extensive research, the common mechanisms driving neurodegeneration
Abbigael Aday, Jack Tiller, Adarsh Melukote, Zachary C. Walton, Anna King, Luke Castillo, Rakez Kayed, Mauro Montalbano   +7 more
wiley   +1 more source

Metabolic Fingerprints of High‐Risk Individuals for Pancreatic Cancer: A Multibiospecimen Investigation

Analysis &Sensing, Volume 6, Issue 4, July 2026.
This study presents a multimatrix untargeted metabolomics analysis of fecal, plasma, and urine samples from individuals at high risk for pancreatic cancer development. Integrated multivariate and cofactor‐adjusted models were applied to characterize cross‐matrix metabolomic associations, incorporating pancreatic magnetic resonance imaging data, sex ...
Vladyslav Dovhalyuk, Quang‐Dong Bui, Vincent Ripoll, Wiktor Rutkowski, Miroslav Vujasinovic, J.‐Matthias Löhr, Daniel Globisch   +6 more
wiley   +1 more source

The Role of Cyclic Diketopiperazine in the Formation of Polypeptides on Silica Surfaces

ChemPlusChem, Volume 91, Issue 7, July 2026.
The parameters governing diketopiperazine (DKP) deposition, reactivity, and opening on amorphous silica are investigated through complementary studies in both liquid and gas phases in the frame of glycine (Gly) polymerization. The results demonstrate that DKP acts as an efficient intermediate toward the formation of linear poly‐Gly, yielding ...
Ola El Samrout, Rita Arnesi, Samuele Mistrali, Chiara Nannuzzi, Gloria Berlier   +4 more
wiley   +1 more source

Inhibition of Candida albicans yeast-to-hypha transition and virulence by cyclic dipeptides derived from probiotic Aeromonas veronii V03. [PDF]

Sci Rep
Sekar J, Parasuraman G, Shanmugam A, Dharumadurai D, Dileep Kumar BS, Natesan S.   +5 more
europepmc   +1 more source

Pam3CSK4 As a Second Hit in NLRP3‐Dependent Activation of Monocytes Primed With Antiphospholipid Antibodies

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Pam3CSK4 amplifies aPL‐induced monocyte activation. This results in thromboinflammatory activation that may contribute to APS‐related vascular pathology. ABSTRACT Antiphospholipid antibodies (aPL) are drivers of inflammation and thrombosis in antiphospholipid syndrome (APS). However, the molecular mechanisms underlying infection‐induced exacerbation of
Anush Martirosyan, Eva Kriegova, Jana Ulehlova, Zaven Karalyan, Tomas Papajik, Gayane Manukyan   +5 more
wiley   +1 more source

In Vivo Atlas of Neuroprotective Cyclic Dipeptides Derived from Food Gelatin Using Peptidomics and Feature-Based Molecular Networking. [PDF]

J Agric Food Chem
Dong P, Ao L, Li Y, Zeng H, Zhang Y, Zou H, Leng J, Li N, Wu JL.   +8 more
europepmc   +1 more source

Nutritional and Compositional Profile of Hypsizygus ulmarius Fruiting Bodies as Affected by Spent Tea Leaves and Spent Coffee Grounds Supplementation

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Supplementation of wheat‐straw substrates with 10%–30% spent tea leaves (STL) or spent coffee grounds (SCG) produced residue‐specific changes in the composition of Hypsizygus ulmarius fruiting bodies. STL supplementation was associated with increased protein, total amino acid content, and CUPRAC values, whereas SCG supplementation was associated with ...
Funda Atila, Mehmet Çetin, Didem Aksu
wiley   +1 more source