Results 191 to 200 of about 4,865 (234)

Cyclic dipeptides: from bugs to brain [PDF]

Trends in Molecular Medicine, 2014
Cyclic dipeptides (CDPs) are a group of hormone-like molecules that are evolutionarily conserved from bacteria to humans. In bacteria, CDPs are used in quorum sensing (QS) to communicate information about population size and to regulate a behavioural switch from symbiosis with their host to virulence.
BELLEZZA, ILARIA, PEIRCE, MATTHEW JOHN, MINELLI, Alba   +2 more
openaire   +3 more sources

Synthesis and evaluation of eight-membered cyclic pseudo-dipeptides [PDF]

Peptides, 2005
In the course of the development of calpain inhibitors, we report the synthesis of eight-membered cyclic pseudo dipeptides closely related to the known inhibitor SJA6017. The ring closure was effected by metathesis of the diallyl-substituted dipeptides 6 and 7. The formation of the dipeptides under kinetic control leads to the preferential formation of
Abell, A., Brown, K., Coxon, J., Jones, M., Miyamoto, S., Neffe, A., Nikkel, J., Stuart, B.   +7 more
openaire   +4 more sources

Fragmentation of deprotonated cyclic dipeptides by electrospray ionization mass spectrometry [PDF]

Journal of Mass Spectrometry, 2009
The fragmentation pathways of deprotonated cyclic dlipeptides have been studied by electrospray ionization multi-stage mass spectrometry (ESI-MS(n)) in negative mode.
Yanchun Guo, Donghui Wei
exaly   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Linear and cyclic dipeptides with antimalarial activity

Bioorganic & Medicinal Chemistry Letters, 2012
Several natural and synthetic polypeptides possess important antimalarial activity. Shorter peptides with potent antimalarial activity have also been described, among them linear di-, tri-, tetra- and pentapeptides and their cyclic analogs. In an attempt to find dipeptides with antimalarial activities we show that linear and cyclic dipeptides, the ...
Lemuel, Pérez-Picaso, Horacio F, Olivo, Rocío, Argotte-Ramos, María, Rodríguez-Gutiérrez, María Yolanda, Rios   +4 more
openaire   +2 more sources

A New Cyclic Dipeptide from Peptone

Nature, 1960
WHILE investigating the antifungal principle derived from cultures of a Bacillus subtilis strain, a crystalline substance was obtained as one of the byproducts. It was necessary to decide whether the crystals were a metabolite of the organism or originally contained in peptone used as a dietary essential.
T, KOSUGE, H, KAMIYA
openaire   +2 more sources

Reversibly Thermochromic Cyclic Dipeptide Nanotubes

Langmuir, 2018
Owing to their capability of forming extensive hydrogen bondings and the facile introduction of chirality, cyclic dipeptides (CDPs) have gained great attention as scaffolds for functional supramolecules. Surprisingly, introduction of a photopolymerizable diacetylene (DA) moiety to the CDP afforded nanotubular structures with enhanced stability and ...
Min Jeong Seo, Jisoo Song, Chandra Kantha, Mohammed Iqbal Khazi, Umesha Kundapur, Jung-Moo Heo, Jong-Man Kim   +6 more
openaire   +2 more sources

Conformational analysis of cyclic dipeptides: I. , , , and

Russian Journal of Bioorganic Chemistry, 2008
Conformational analysis of two pairs of synthetic cyclodipeptides formed by interaction of both side chain functional groups [Formula: see text] and of the main and side chains [Formula: see text] was achieved by the method of molecular mechanics. The energetically optimal conformational states of the molecules under study were determined. It was shown
S F, Arkhipova, I V, Artem'ev, E A, Goriacheva, V Z, Pletnev   +3 more
openaire   +2 more sources

EMPIRICAL CALCULATIONS ON CYCLIC DIPEPTIDES

International Journal of Peptide and Protein Research, 1980
Empirical conformational energy calculations were carried out for the dipeptides cyclo‐(L‐Asp‐L‐His) and cyclo‐(L‐Glu‐L‐His). The side chain conformations have been studied for various DKP ring structures, demonstrating that distortions can modify the stability of some conformations by favouring peptide backboneside chain or side chain ‐ side chain ...
M. GENEST, M. PTAK
openaire   +1 more source

Cyclic dipeptides exhibit potency for scavenging radicals

Bioorganic & Medicinal Chemistry, 2012
Twenty kinds of cyclic dipeptides containing l-leucine were synthesized, and their antioxidant activity against ·OH and O(2)(·-) was investigated. Compounds possessing polar amino acid residues, such as Asp, Cys, Glu, Lys, Pro, Ser, and Trp, exhibited higher antioxidant activity against ·OH than vitamin E. However, only cyclo(l-Cys-l-Leu) scavenged O(2)
Tadashi, Furukawa, Takashi, Akutagawa, Hitomi, Funatani, Toshikazu, Uchida, Yoshihiro, Hotta, Masatake, Niwa, Yoshiaki, Takaya   +6 more
openaire   +2 more sources

The optical properties of tyrosine‐containing cyclic dipeptides

Biopolymers, 1977
AbstractThe chiroptical properties of the cyclic dipeptides cyclo (L‐alanyl‐L‐tyrosine) and cyclo(L‐tyrosyl‐L‐tyrosine) have been investigated as a function of molecular conformation. Theoretical optical calculations and conformational energy calculations have been carried out as a function of the side‐chain dihedral angles χ1 and χ2, and as a function
J W, Snow, T M, Hooker, J A, Schellman
openaire   +2 more sources